Pathophysiology of type 2 diabetes mellitus

U Galicia-Garcia, A Benito-Vicente, S Jebari… - International journal of …, 2020 - mdpi.com
Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused
by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and …

Hepatic cholesterol transport and its role in non-alcoholic fatty liver disease and atherosclerosis

H Li, XH Yu, X Ou, XP Ouyang, CK Tang - Progress in lipid research, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …

Dyslipidemia and cardiovascular disease risk among the MASHAD study population

M Hedayatnia, Z Asadi, R Zare-Feyzabadi… - Lipids in health and …, 2020 - Springer
Introduction Dyslipidemia may be defined as increased levels of serum total cholesterol
(TC), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), or a decreased serum …

Association between high-density lipoprotein cholesterol levels and adverse cardiovascular outcomes in high-risk populations

C Liu, D Dhindsa, Z Almuwaqqat, YA Ko… - JAMA …, 2022 - jamanetwork.com
Importance Previous studies have shown lower cardiovascular risk with higher high-density
lipoprotein cholesterol (HDL-C) levels. However, recent data in the general population have …

Overview of epidemiology and contribution of obesity to cardiovascular disease

M Bastien, P Poirier, I Lemieux, JP Després - Progress in cardiovascular …, 2014 - Elsevier
The prevalence of obesity has increased worldwide and is a source of concern since the
negative consequences of obesity start as early as in childhood. The most commonly used …

Effects of dalcetrapib in patients with a recent acute coronary syndrome

GG Schwartz, AG Olsson, M Abt… - … England Journal of …, 2012 - Mass Medical Soc
Background In observational analyses, higher levels of high-density lipoprotein (HDL)
cholesterol have been associated with a lower risk of coronary heart disease events …

[HTML][HTML] High-density lipoprotein (HDL) functionality and its relevance to atherosclerotic cardiovascular disease

CE Kosmas, I Martinez, A Sourlas, KV Bouza… - Drugs in …, 2018 - ncbi.nlm.nih.gov
Several prospective epidemiological studies have shown that there is a clear inverse
relationship between serum high-density lipoprotein-cholesterol (HDL-C) concentrations …

High-density lipoproteins: nature's multifunctional nanoparticles

R Kuai, D Li, YE Chen, JJ Moon, A Schwendeman - ACS nano, 2016 - ACS Publications
High-density lipoproteins (HDL) are endogenous nanoparticles involved in the transport and
metabolism of cholesterol, phospholipids, and triglycerides. HDL is well-known as the …

Immune dysfunction in uremia 2020

G Cohen - Toxins, 2020 - mdpi.com
Cardiovascular disease and infections are major causes for the high incidence of morbidity
and mortality of patients with chronic kidney disease. Both complications are directly or …