Neuromodulation for pain management

J Wang, Z Chen - Neural Interface: Frontiers and Applications, 2019 - Springer
Pain is a salient and complex sensory experience with important affective and cognitive
dimensions. The current definition of pain relies on subjective reports in both humans and …

Temporal pain processing in the primary somatosensory cortex and anterior cingulate cortex

G Sun, M McCartin, W Liu, Q Zhang, G Kenefati… - Molecular Brain, 2023 - Springer
Pain is known to have sensory and affective components. The sensory pain component is
encoded by neurons in the primary somatosensory cortex (S1), whereas the emotional or …

Decoding pain from brain activity

ZS Chen - Journal of Neural Engineering, 2021 - iopscience.iop.org
Pain is a dynamic, complex and multidimensional experience. The identification of pain from
brain activity as neural readout may effectively provide a neural code for pain, and further …

Rate and temporal coding mechanisms in the anterior cingulate cortex for pain anticipation

L Urien, Z **ao, J Dale, EP Bauer, Z Chen, J Wang - Scientific reports, 2018 - nature.com
Pain is a complex sensory and affective experience. Through its anticipation, animals can
learn to avoid pain. Much is known about passive avoidance during a painful event; …

Real-time particle filtering and smoothing algorithms for detecting abrupt changes in neural ensemble spike activity

S Hu, Q Zhang, J Wang, Z Chen - Journal of …, 2018 - journals.physiology.org
Sequential change-point detection from time series data is a common problem in many
neuroscience applications, such as seizure detection, anomaly detection, and pain …

Ensembles of change-point detectors: implications for real-time BMI applications

Z **ao, S Hu, Q Zhang, X Tian, Y Chen, J Wang… - Journal of computational …, 2019 - Springer
Brain-machine interfaces (BMIs) have been widely used to study basic and translational
neuroscience questions. In real-time closed-loop neuroscience experiments, many practical …

A real-time rodent neural interface for deciphering acute pain signals from neuronal ensemble spike activity

S Hu, Q Zhang, J Wang, Z Chen - 2017 51st Asilomar …, 2017 - ieeexplore.ieee.org
In recent years, brain machine interfaces have attracted accumulating interest with goals to
map, assist, augment or repair the cognitive or sensory-motor functions of human and …

Real-time detection of acute pain signals based on spikes/LFP

ZS Chen - Handbook of Neuroengineering, 2021 - Springer
Acute pain is triggered by noxious stimuli that induce changes in neural responses of
specific neural circuits at both single neuron and population levels. Detecting acute pain …

Latent variable modeling of neural population dynamics

Z Chen - Dynamic Neuroscience: Statistics, Modeling, and …, 2018 - Springer
A fundamental task in neural data analysis is to discover the regularity or structure of
measured (potentially high-dimensional) neural data. Measurements of neural activity …

Real-time particle filtering and smoothing algorithms for

S Hu, Q Zhang, J Wang, Z Chen - journals.physiology.org
NEW & NOTEWORTHY Sequential change-point detection is an important problem 38 in
closed-loop neuroscience experiments. This study proposes novel sequential Monte Carlo …