Mechanochemistry: new tools to navigate the uncharted territory of “impossible” reactions

F Cuccu, L De Luca, F Delogu, E Colacino… - …, 2022 - Wiley Online Library
Mechanochemical transformations have made chemists enter unknown territories, forcing a
different chemistry perspective. While questioning or revisiting familiar concepts belonging …

Novel methodologies for chemical activation in organic synthesis under solvent-free reaction conditions

CG Avila-Ortiz, E Juaristi - Molecules, 2020 - mdpi.com
One central challenge for XXI century chemists is the development of sustainable processes
that do not represent a risk either to humanity or to the environment. In this regard, the …

Metal-mediated and metal-catalyzed reactions under mechanochemical conditions

A Porcheddu, E Colacino, L De Luca, F Delogu - ACS Catalysis, 2020 - ACS Publications
The extraordinary impact of metal-based complexes on synthetic methods is still recognized
nowadays, and attempts are currently undertaken to further extend the use of metal-assisted …

Mineral-mediated carbohydrate synthesis by mechanical forces in a primordial geochemical setting

M Haas, S Lamour, SB Christ, O Trapp - Communications Chemistry, 2020 - nature.com
The formation of carbohydrates represents an essential step to provide building blocks and
a source of chemical energy in several models for the emergence of life. Formaldehyde …

Mechanochemistry for Organic and Inorganic Synthesis

JF Reynes, F Leon, F García - ACS Organic & Inorganic Au, 2024 - ACS Publications
In recent years, mechanochemistry has become an innovative and sustainable alternative to
traditional solvent-based synthesis. Mechanochemistry rapidly expanded across a wide …

The “η-sweet-spot”(η max) in liquid-assisted mechanochemistry: polymorph control and the role of a liquid additive as either a catalyst or an inhibitor in resonant …

L Gonnet, TH Borchers, CB Lennox, J Vainauskas… - Faraday …, 2023 - pubs.rsc.org
Resonant acoustic mixing (RAM) offers a simple, efficient route for mechanochemical
synthesis in the absence of milling media or bulk solvents. Here, we show the use of RAM to …

Mechanochemistry in transition metal-catalyzed reactions

F Effaty, X Ottenwaelder, T Friščić - Current Opinion in Green and …, 2021 - Elsevier
Over the past 15 years, mechanochemistry has developed into a powerful tool for the
synthesis of molecules and materials while avoiding the consumption of bulk solvents. With …

The use of copper and vanadium mineral ores in catalyzed mechanochemical carbon–carbon bond formations

F Puccetti, C Schumacher, H Wotruba… - ACS Sustainable …, 2020 - ACS Publications
Under mechanochemical conditions in ball mills, copper-and vanadium-containing minerals
initiate atom transfer radical cyclizations and oxidative couplings, respectively. Only catalytic …

Mechanochemistry as a tool for crystallizing inaccessible solids from viscous liquid components

JD Loya, SJ Li, DK Unruh, KM Hutchins - Crystal Growth & Design, 2021 - ACS Publications
The crystal structures of many organic compounds can be determined by growing single
crystals using standard laboratory methods and collecting X-ray data using single-crystal X …

Exploring the in situ formation mechanism of polymeric aluminum chloride–silica gel composites under mechanical grinding conditions: as a high-performance …

G Wang, Y Geng, Z Zhao, Q Zhang, X Li, Z Wu, S Bi… - ACS …, 2022 - ACS Publications
The use of mechanical ball milling to facilitate the synthesis of organic compounds has
attracted intense interest from organic chemists. Herein, we report a new process for the …