Hyaluronic acid hydrogels for biomedical applications

JA Burdick, GD Prestwich - Advanced materials, 2011 - Wiley Online Library
Hyaluronic acid (HA), an immunoneutral polysaccharide that is ubiquitous in the human
body, is crucial for many cellular and tissue functions and has been in clinical use for over …

Hyaluronan: a simple polysaccharide with diverse biological functions

KT Dicker, LA Gurski, S Pradhan-Bhatt, RL Witt… - Acta biomaterialia, 2014 - Elsevier
Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid
and N-acetyl-d-glucosamine. It is evolutionarily conserved and abundantly expressed in the …

Hyaluronic acid-based hydrogels: from a natural polysaccharide to complex networks

X Xu, AK Jha, DA Harrington, MC Farach-Carson, X Jia - Soft matter, 2012 - pubs.rsc.org
Hyaluronic acid (HA) is one of nature's most versatile and fascinating macromolecules.
Being an essential component of the natural extracellular matrix (ECM), HA plays an …

[HTML][HTML] In situ self-assembled organoid for osteochondral tissue regeneration with dual functional units

Z Yang, B Wang, W Liu, X Li, K Liang, Z Fan, JJ Li… - Bioactive Materials, 2023 - Elsevier
The regeneration of hierarchical osteochondral units is challenging due to difficulties in
inducing spatial, directional and controllable differentiation of mesenchymal stem cells …

Hyaluronic acid-based clinical biomaterials derived for cell and molecule delivery in regenerative medicine

GD Prestwich - Journal of controlled release, 2011 - Elsevier
The development of injectable and biocompatible vehicles for delivery, retention, growth,
and differentiation of stem cells is of paramount importance for regenerative medicine. For …

Perlecan, a multi-functional, cell-instructive, matrix-stabilizing proteoglycan with roles in tissue development has relevance to connective tissue repair and …

AJ Hayes, BL Farrugia, IJ Biose, GJ Bix… - Frontiers in Cell and …, 2022 - frontiersin.org
This review highlights the multifunctional properties of perlecan (HSPG2) and its potential
roles in repair biology. Perlecan is ubiquitous, occurring in vascular, cartilaginous, adipose …

Extracellular matrix‐based strategies for immunomodulatory biomaterials engineering

AT Rowley, RR Nagalla, SW Wang… - Advanced healthcare …, 2019 - Wiley Online Library
The extracellular matrix (ECM) is a complex and dynamic structural scaffold for cells within
tissues and plays an important role in regulating cell function. Recently it has become …

Tissue engineering strategies for promoting vascularized bone regeneration

S Almubarak, H Nethercott, M Freeberg, C Beaudon… - Bone, 2016 - Elsevier
This review focuses on current tissue engineering strategies for promoting vascularized
bone regeneration. We review the role of angiogenic growth factors in promoting …

Sulfated polysaccharide-based scaffolds for orthopaedic tissue engineering

J Dinoro, M Maher, S Talebian, M Jafarkhani… - Biomaterials, 2019 - Elsevier
Given their native-like biological properties, high growth factor retention capacity and porous
nature, sulfated-polysaccharide-based scaffolds hold great promise for a number of tissue …

The potential applications of hyaluronic acid hydrogels in biomedicine

E Ahmadian, SM Dizaj, A Eftekhari, E Dalir… - Drug …, 2020 - thieme-connect.com
Hyaluronic acid (HA) is widely used in the biomedicine due to its biocompatibility,
biodegradability, and nontoxic properties. It is crucial for cell signaling role during …