Cardiac arrhythmias are among the leading causes of mortality. They often arise from
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …

The thyroid-stimulating hormone receptor (TSH-R) is predominantly expressed in the
basolateral membrane of thyrocytes, where it stimulates almost every aspect of their …

Subclinical thyroid dysfunction (STD), presenting as subclinical hypothyroidism (SHypo) or
subclinical hyperthyroidism (SHyper), defined as abnormal serum thyrotropin (TSH) and …

It is well established that thyroid dysfunction is linked to an increased risk of cardiovascular
morbidity and mortality. The pleiotropic action of thyroid hormones strongly impacts the …

Hypothyroidism is the most frequent endocrine pathology. Although clinical or overt
hypothyroidism has been traditionally associated to low T3/T4 and high thyrotropin (TSH) …

There is an intimate and functional relationship between the cardiovascular system and the
thyroid gland; from sharing the same embryologic origin to modulating each of the …

Thyroid dysfunction is the most prevalent endocrine disorder worldwide having an
epidemiology of 11% in Indians, 4.6% in the United Kingdom, and 2% in the United States of …

Importance Thyroid hormone levels are tightly regulated through feedback inhibition by
thyrotropin, produced by the pituitary gland. Hyperthyroidism is overwhelmingly due to …

TSHR is a member of the glycoprotein hormone receptors, a subfamily of class A G-protein-
coupled receptors and plays pivotal roles in various physiological and pathological …

Purpose It is well known that hyperthyroidism is associated with atrial fibrillation (AF);
however, the relationship between hypothyroidism and AF remains controversial. Methods …