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Chemometrics in metabonomics
We provide an overview of how the underlying philosophy of chemometrics is integrated
throughout metabonomic studies. Four steps are demonstrated:(1) definition of the aim,(2) …
throughout metabonomic studies. Four steps are demonstrated:(1) definition of the aim,(2) …
NMR and pattern recognition methods in metabolomics: from data acquisition to biomarker discovery: a review
Metabolomics is the discipline where endogenous and exogenous metabolites are
assessed, identified and quantified in different biological samples. Metabolites are crucial …
assessed, identified and quantified in different biological samples. Metabolites are crucial …
Metabolomics-based methods for early disease diagnostics
The emerging field of metabolomics, in which a large number of small-molecule metabolites
from body fluids or tissues are detected quantitatively in a single step, promises immense …
from body fluids or tissues are detected quantitatively in a single step, promises immense …
Chemometrics in metabolomics—a review in human disease diagnosis
R Madsen, T Lundstedt, J Trygg - Analytica chimica acta, 2010 - Elsevier
Metabolomics is a post genomic research field concerned with develo** methods for
analysis of low molecular weight compounds in biological systems, such as cells, organs or …
analysis of low molecular weight compounds in biological systems, such as cells, organs or …
Targeted metabolomics for biomarker discovery
Metabolomics is a truly interdisciplinary field of science, which combines analytical
chemistry, platform technology, mass spectrometry, and NMR spectroscopy with …
chemistry, platform technology, mass spectrometry, and NMR spectroscopy with …
NMR-based metabolomics in human disease diagnosis: applications, limitations, and recommendations
Metabolomics is a dynamic and emerging research field, similar to proteomics,
transcriptomics and genomics in affording global understanding of biological systems. It is …
transcriptomics and genomics in affording global understanding of biological systems. It is …
Comparing and combining NMR spectroscopy and mass spectrometry in metabolomics
Z Pan, D Raftery - Analytical and bioanalytical chemistry, 2007 - Springer
The rapidly expanding field of metabolomics has been driven in recent years by advances in
the analytical methods of high-resolution nuclear magnetic resonance (NMR) spectroscopy …
the analytical methods of high-resolution nuclear magnetic resonance (NMR) spectroscopy …
Standardizing the experimental conditions for using urine in NMR-based metabolomic studies with a particular focus on diagnostic studies: a review
The metabolic composition of human biofluids can provide important diagnostic and
prognostic information. Among the biofluids most commonly analyzed in metabolomic …
prognostic information. Among the biofluids most commonly analyzed in metabolomic …
Normalization strategies for metabonomic analysis of urine samples
BM Warrack, S Hnatyshyn, KH Ott, MD Reily… - … of Chromatography B, 2009 - Elsevier
Unlike plasma and most biological fluids which have solute concentrations that are tightly
controlled, urine volume can vary widely based upon water consumption and other …
controlled, urine volume can vary widely based upon water consumption and other …
[HTML][HTML] The olive constituent oleuropein exhibits anti-ischemic, antioxidative, and hypolipidemic effects in anesthetized rabbits
Thgoal of this study was to evaluate the efficacy of the antioxidant olive constituent,
oleuropein, on infarct size, oxidative damage, and the metabolic profile in rabbits subjected …
oleuropein, on infarct size, oxidative damage, and the metabolic profile in rabbits subjected …