Background. The social rank theory of psychopathology suggests that with the evolution of
social hierarchies various psychobiological mechanisms became attuned to the success or …

Depression is one of the most disabling medical conditions in the world today, yet its
etiologies remain unclear and current treatments are not wholly effective. Animal models are …

Stress, especially chronic stress, is one of the most important factors responsible for
precipitation of affective disorders in humans. The animal models commonly used in the …

While light is considered the dominant stimulus for entraining (synchronizing) mammalian
circadian rhythms to local environmental time, social stimuli are also widely cited as …

Circadian rhythms influence most of our life activities, notably getting up and going to sleep
every day. The new edition of this book delves into the mechanisms surrounding how these …

Many symptoms of human depressive disorders are also observed in animals after exposure
to unpredictable stressors. The chronic mild stress (CMS) paradigm was developed in order …

The impact of ostensibly aversive social stresses on triggering, amplifying and prolonging
intensely rewarding drug taking is an apparent contradiction in need of resolution. Social …

Purpose. The objective of this paper was to evaluate the Cry of Pain model of suicide
behaviour as applied to psychosis and to derive theoretically driven guidelines for …

In mammals, the circadian and stress systems (both centers of which are located in the
hypothalamus) are involved in adaptation to predictable and unpredictable environmental …

This paper summarises the available evidence that failure of defense mechanisms in (semi)-
natural social groups of animals may lead to serious forms of stress pathology. Hence the …