Connecting copper and cancer: from transition metal signalling to metalloplasia

EJ Ge, AI Bush, A Casini, PA Cobine, JR Cross… - Nature Reviews …, 2022 - nature.com
Copper is an essential nutrient whose redox properties make it both beneficial and toxic to
the cell. Recent progress in studying transition metal signalling has forged new links …

Triple-negative breast cancer molecular subty** and treatment progress

L Yin, JJ Duan, XW Bian, S Yu - Breast Cancer Research, 2020 - Springer
Triple-negative breast cancer (TNBC), a specific subtype of breast cancer that does not
express estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth …

Epidemiology of brain metastases and leptomeningeal disease

N Lamba, PY Wen, AA Aizer - Neuro-oncology, 2021 - academic.oup.com
Brain metastases affect a significant percentage of patients with advanced extracranial
malignancies. Yet, the incidence of brain metastases remains poorly described, largely due …

Triple negative breast cancer: updates on classification and treatment in 2021

M Bou Zerdan, T Ghorayeb, F Saliba, S Allam… - Cancers, 2022 - mdpi.com
Simple Summary Triple negative breast cancer (TNBC) represents 15 to 20% of all breast
cancers in the United States. The main treatment option remains chemotherapy, despite …

Treatment strategies for breast cancer brain metastases

C Bailleux, L Eberst, T Bachelot - British journal of cancer, 2021 - nature.com
Brain metastases from breast cancer (BCBM) constitute the second most common cause of
brain metastasis (BM), and the incidence of these frequently lethal lesions is currently …

Incidence and prognosis of patients with brain metastases at diagnosis of systemic malignancy: a population-based study

DN Cagney, AM Martin, PJ Catalano, AJ Redig… - Neuro …, 2017 - academic.oup.com
Background Brain metastases are associated with significant morbidity and mortality.
Population-level data describing the incidence and prognosis of patients with brain …

Effect of capecitabine maintenance therapy using lower dosage and higher frequency vs observation on disease-free survival among patients with early-stage triple …

X Wang, SS Wang, H Huang, L Cai, L Zhao, RJ Peng… - Jama, 2021 - jamanetwork.com
Importance Among all subtypes of breast cancer, triple-negative breast cancer has a
relatively high relapse rate and poor outcome after standard treatment. Effective strategies to …

The incidence of brain metastases among patients with metastatic breast cancer: a systematic review and meta-analysis

M Kuksis, Y Gao, W Tran, C Hoey, A Kiss… - Neuro …, 2021 - academic.oup.com
Background Patients with metastatic breast cancer (MBC) are living longer, but the
development of brain metastases often limits their survival. We conducted a systematic …

[HTML][HTML] Current approaches in treatment of triple-negative breast cancer

HA Wahba, HA El-Hadaad - Cancer biology & medicine, 2015 - ncbi.nlm.nih.gov
Triple-negative breast cancer (TNBC) is diagnosed more frequently in younger and
premenopausal women and is highly prevalent in African American women. TNBC is a term …

Triple negative breast cancer: emerging therapeutic modalities and novel combination therapies

A Lee, MBA Djamgoz - Cancer treatment reviews, 2018 - Elsevier
Triple negative breast cancer (TNBC) is a complex and aggressive subtype of breast cancer
which lacks oestrogen receptors, progesterone receptors and HER2 amplification, thereby …