PD-1 and PD-L1 checkpoint signaling inhibition for cancer immunotherapy: mechanism, combinations, and clinical outcome
Several cancers are highly refractory to conventional chemotherapy. The survival of tumors
in several cases is assisted by checkpoint immunomodulation to maintain the imbalance …
in several cases is assisted by checkpoint immunomodulation to maintain the imbalance …
Stimulus-responsive polymeric nanogels as smart drug delivery systems
Nanogels are three-dimensional nanoscale networks formed by physically or chemically
cross-linking polymers. Nanogels have been explored as drug delivery systems due to their …
cross-linking polymers. Nanogels have been explored as drug delivery systems due to their …
pH-Sensitive nanogels for drug delivery in cancer therapy
Z Li, J Huang, J Wu - Biomaterials Science, 2021 - pubs.rsc.org
As a commonly used treatment method for cancer, chemotherapy is greatly limited by the
side effects of chemotherapy drugs and the multiple drug resistance that develops …
side effects of chemotherapy drugs and the multiple drug resistance that develops …
Anticancer drugs: recent strategies to improve stability profile, pharmacokinetic and pharmacodynamic properties
G Ioele, M Chieffallo, MA Occhiuzzi, M De Luca… - Molecules, 2022 - mdpi.com
In past decades, anticancer research has led to remarkable results despite many of the
approved drugs still being characterized by high systemic toxicity mainly due to the lack of …
approved drugs still being characterized by high systemic toxicity mainly due to the lack of …
Recent biomedical approaches for chitosan based materials as drug delivery nanocarriers
In recent decades, drug delivery systems (DDSs) based on nanotechnology have been
attracting substantial interest in the pharmaceutical field, especially those developed based …
attracting substantial interest in the pharmaceutical field, especially those developed based …
Polymer-based smart drug delivery systems for skin application and demonstration of stimuli-responsiveness
L Van Gheluwe, I Chourpa, C Gaigne, E Munnier - Polymers, 2021 - mdpi.com
Progress in recent years in the field of stimuli-responsive polymers, whose properties
change depending on the intensity of a signal, permitted an increase in smart drug delivery …
change depending on the intensity of a signal, permitted an increase in smart drug delivery …
Recent developments in stimuli-responsive polymer nanogels for drug delivery and diagnostics: A review
NK Preman, RR Barki, A Vijayan, SG Sanjeeva… - European Journal of …, 2020 - Elsevier
Polymer nanogels (NGs) are water-swellable, cross-linked 3D network structures with size
typically range from 1 to 1000 nm. Especially, biocompatible and “smart” NGs engineered …
typically range from 1 to 1000 nm. Especially, biocompatible and “smart” NGs engineered …
Polysaccharide-based nanogels for biomedical applications: A comprehensive review
The biomedical, biotech, and food industries all use polysaccharides as vital biomolecules
with a variety of applications. Polysaccharides have a great deal of potential as biomaterials …
with a variety of applications. Polysaccharides have a great deal of potential as biomaterials …
Advancement in nanogel formulations provides controlled drug release
Nanogels are currently considered as promising nanosized drug delivery carriers. Nanogels
are made of a crosslinked polymeric network which could encapsulate both hydrophilic and …
are made of a crosslinked polymeric network which could encapsulate both hydrophilic and …
Multifunctional nanoparticles for cancer immunotherapy: A groundbreaking approach for reprogramming malfunctioned tumor environment
Several cancer immunotherapy approaches have been recently introduced into the clinics
and they have shown remarkable therapeutic potentials. The groundbreaking cancer …
and they have shown remarkable therapeutic potentials. The groundbreaking cancer …