This article describes the pathways of eicosanoid synthesis, eicosanoid receptors, the action
of eicosanoids in different physiological systems, the roles of eicosanoids in selected …

Polyunsaturated fatty acids (PUFAs) are important components of the diet of mammals. Their
role was first established when the essential fatty acids (EFAs) linoleic acid and α-linolenic …

The antioxidant, anti-inflammatory and antibacterial activities of hesperetin, hesperidin and
hesperidin glucoside with different solubility were compared in vitro. Hesperetin was …

Neutrophils, the most abundant innate immune cells, function as crucial regulators of the
adaptive immune system in diverse pathological conditions, including metastatic cancer …

Protease inhibitors can modulate intratumoral metabolic processes to reprogram the
immunosuppressive tumor microenvironment (TME), which however suffer from the limited …

Profound and debilitating fatigue is the most common complaint reported among individuals
with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 …

Many chronic conditions such as cancer, chronic obstructive pulmonary disease, type-2
diabetes, obesity, peripheral/coronary artery disease and auto-immune diseases are …

Colonocyte metabolism shapes the microbiome. Metabolites are the main mediators of
information exchange between intestine and microbial communities. Arachidonic acid (AA) …

The immune system is complex: it involves many cell types and numerous chemical
mediators. An immature immune response increases susceptibility to infection, whilst …

The effects of rutin and rutin glycoside with different solubility were compared on antioxidant
activity and anti-inflammatory effects in vitro and the effects on platelet aggregation and …