Formation of the human heart involves complex biological signals, interactions, specification
of myocardial progenitor cells, and heart tube loo**. To facilitate survival in the hypoxemic …

In this review, we focus on two important steps in the formation of the embryonic heart:(i) the
progressive addition of late differentiating progenitor cells from the second heart field that …

The heart automaticity is a fundamental physiological function in higher organisms. The
spontaneous activity is initiated by specialized populations of cardiac cells generating …

The heart is the first organ to form during embryonic development. Given the complex nature
of cardiac differentiation and morphogenesis, it is not surprising that some form of congenital …

The myocardium of the heart is composed of multiple highly specialized myocardial
lineages, including those of the ventricular and atrial myocardium, and the specialized …

The multi-chambered mammalian heart arises from a simple tube by polar elongation,
myocardial differentiation and morphogenesis. Members of the large family of T-box (Tbx) …

Background Childhood-onset pulmonary arterial hypertension (PAH) is rare and differs from
adult-onset disease in clinical presentation, with often unexplained mental retardation and …

Early cardiac development involves the formation of a heart tube, loo** of the tube and
formation of chambers. These processes are highly similar among all vertebrates, which …

The cardiac conduction system consists of distinctive heart muscle cells that initiate and
propagate the electric impulse required for coordinated contraction. The conduction system …

The conduction system of the heart initiates and coordi-nates the electric signal that causes
the rhythmic and synchronized contractions of the atria and ventricles. In higher vertebrates …