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Assessing the mechanisms of brain plasticity by transcranial magnetic stimulation
Transcranial magnetic stimulation (TMS) is a non-invasive technique for focal brain
stimulation based on electromagnetic induction where a fluctuating magnetic field induces a …
stimulation based on electromagnetic induction where a fluctuating magnetic field induces a …
Sensory perception in autism
Autism is a complex neurodevelopmental condition, and little is known about its
neurobiology. Much of autism research has focused on the social, communication and …
neurobiology. Much of autism research has focused on the social, communication and …
Autism genes converge on asynchronous development of shared neuron classes
Genetic risk for autism spectrum disorder (ASD) is associated with hundreds of genes
spanning a wide range of biological functions,,,,–. The alterations in the human brain …
spanning a wide range of biological functions,,,,–. The alterations in the human brain …
The role of GABAergic signalling in neurodevelopmental disorders
GABAergic inhibition shapes the connectivity, activity and plasticity of the brain. A series of
exciting new discoveries provides compelling evidence that disruptions in a number of key …
exciting new discoveries provides compelling evidence that disruptions in a number of key …
mTOR-related synaptic pathology causes autism spectrum disorder-associated functional hyperconnectivity
Postmortem studies have revealed increased density of excitatory synapses in the brains of
individuals with autism spectrum disorder (ASD), with a putative link to aberrant mTOR …
individuals with autism spectrum disorder (ASD), with a putative link to aberrant mTOR …
The valproic acid-induced rodent model of autism
Autism is a lifelong neurodevelopmental disorder characterized by impairments in social
communication and interaction and by repetitive patterns of behavior, interests and activities …
communication and interaction and by repetitive patterns of behavior, interests and activities …
Autism spectrum disorder: neuropathology and animal models
Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An …
integration of affected individuals and is the most heritable of psychiatric disorders. An …
[HTML][HTML] Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits
Developmental alterations of excitatory synapses are implicated in autism spectrum
disorders (ASDs). Here, we report increased dendritic spine density with reduced …
disorders (ASDs). Here, we report increased dendritic spine density with reduced …
[HTML][HTML] Excitation/inhibition imbalance in animal models of autism spectrum disorders
Imbalances between excitation and inhibition in synaptic transmission and neural circuits
have been implicated in autism spectrum disorders. Excitation and inhibition imbalances are …
have been implicated in autism spectrum disorders. Excitation and inhibition imbalances are …
Stress and the social brain: behavioural effects and neurobiological mechanisms
Stress often affects our social lives. When undergoing high-level or persistent stress,
individuals frequently retract from social interactions and become irritable and hostile …
individuals frequently retract from social interactions and become irritable and hostile …