Positive associations between human intelligence and brain size have been suspected for
more than 150 years. Nowadays, modern non-invasive measures of in vivo brain volume …

Comparative analyses are the backbone of evolutionary analysis. However, their record in
producing a consensus has not always been good. This is especially true of attempts to …

The highly complex structure of the human brain is strongly shaped by genetic influences.
Subcortical brain regions form circuits with cortical areas to coordinate movement, learning …

The challenge of precision medicine is to model complex interactions among DNA variants,
phenotypes, development, environments, and treatments. We address this challenge by …

The develo** human brain remains one of the few unsolved mysteries of science.
Advancements in developmental biology, neuroscience and medical imaging have brought …

Phenotypic traits are products of two processes: evolution and development. But how do
these processes combine to produce integrated phenotypes? Comparative studies identify …

Despite prolonged interest in comparing brain size and behavioral proxies of
'intelligence'across taxa, the adaptive and cognitive significance of brain size variation …

Expansion of the neocortex is a hallmark of human evolution. However, determining which
adaptive mechanisms facilitated its expansion remains an open question. Here we show …

The brain is a trait of central importance for organismal performance and fitness. To date,
evolutionary studies of brain size variation have mainly utilized comparative methods …

A central question in brain evolution is how species-typical behaviors, and the neural
function-structure map**s supporting them, can be acquired and inherited. Advocates of …