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Furan and benzofuran derivatives as privileged scaffolds as anticancer agents: SAR and docking studies (2010 to till date)
Furan and benzofuran scaffolds are privileged and well-studied heterocyclic rings for
designing and develo** new potential anticancer compounds. Previous literature showed …
designing and develo** new potential anticancer compounds. Previous literature showed …
4‐Hydroxycoumarin: A versatile substrate for transition‐metal‐free multicomponent synthesis of bioactive heterocycles
One‐pot multi‐component reactions especially under transition‐metal‐free catalysis served
as an efficient, and environmentally friendly method for the construction of value‐added …
as an efficient, and environmentally friendly method for the construction of value‐added …
[HTML][HTML] Total Flavonoids in Artemisia absinthium L. and Evaluation of Its Anticancer Activity
M He, K Yasin, S Yu, J Li, L **a - International Journal of Molecular …, 2023 - mdpi.com
To overcome the shortcomings of traditional extraction methods, such as long extraction time
and low efficiency, and considering the low content and high complexity of total flavonoids in …
and low efficiency, and considering the low content and high complexity of total flavonoids in …
Novel butenolide derivatives as dual-chitinase inhibitors to arrest the growth and development of the Asian corn borer
R Zou, X Li, X Jiang, D Shi, Q Han… - Journal of Agricultural …, 2024 - ACS Publications
Of ChtI and Of Chi-h are considered potential targets for the control of Asian corn borer
(Ostrinia furnacalis). In this work, the previously reported Of ChtI inhibitor 5f was found to …
(Ostrinia furnacalis). In this work, the previously reported Of ChtI inhibitor 5f was found to …
[HTML][HTML] Conjugation as a tool in therapeutics: Role of amino acids/peptides-bioactive (including Heterocycles) hybrid molecules in treating infectious diseases
R Gattu, SS Ramesh, S Nadigar, S Ramesh - Antibiotics, 2023 - mdpi.com
Peptide-based drugs are gaining significant momentum in the modern drug discovery, which
is witnessed by the approval of new drugs by the FDA in recent years. On the other hand …
is witnessed by the approval of new drugs by the FDA in recent years. On the other hand …
A review on biological and medicinal significance of furan
H Saeid, H Al-sayed, M Bader - AlQalam Journal of Medical and Applied …, 2023 - uta.edu.ly
An important group of heterocyclic compounds with significant biological characteristics are
furan derivatives. The creation of furan derivatives and their testing for various …
furan derivatives. The creation of furan derivatives and their testing for various …
[HTML][HTML] Synthesis of Second-Generation Analogs of Temporin-SHa Peptide Having Broad-Spectrum Antibacterial and Anticancer Effects
Antimicrobial peptides (AMPs) are a promising class of therapeutic alternatives with broad-
spectrum activity against resistant pathogens. Small AMPs like temporin-SHa (1) and its first …
spectrum activity against resistant pathogens. Small AMPs like temporin-SHa (1) and its first …
Enantioselective Friedel–Crafts Alkylation of Furans with o-Quinone Methide Using a Chiral Oxazaborolidinium Ion Catalyst
YS Cho, ST Kim, DH Ryu - Organic Letters, 2022 - ACS Publications
A chiral Lewis acid-catalyzed enantioselective Friedel–Crafts furan alkylation with in situ-
generated o-quinone methides has been developed. In the presence of a chiral …
generated o-quinone methides has been developed. In the presence of a chiral …
Anti-tumor effects of novel alkannin derivatives with potent selectivity on comprehensive analysis
Z Dai, F Gao, Z Zhang, M Lu, Y Luo, T Zhang, B Shang… - Phytomedicine, 2023 - Elsevier
Background Therapeutic approaches based on glycolysis and energy metabolism of tumor
cells are new promising strategies for the treatment of cancer. Currently, researches on the …
cells are new promising strategies for the treatment of cancer. Currently, researches on the …
Comparative DNA-/BSA-binding, DNA cleavage, and cytotoxic properties of copper (II) amino/salicyl-phenolate Schiff bases (phen) complexes that induce generation …
A Mamindla, M Varadhan, R Kartikeyan… - Polyhedron, 2023 - Elsevier
A series of mixed-ligand Cu (II) complexes of the type [Cu (L 1-5)(diimine)(H 2 O)](ClO 4)(1–
5) and [Cu (L 6)(diimine)](ClO 4)(6), where HL 1-HL 4 are aminophenolate Schiff base …
5) and [Cu (L 6)(diimine)](ClO 4)(6), where HL 1-HL 4 are aminophenolate Schiff base …