Dendritic peptide release and peptide-dependent behaviours

M Ludwig, G Leng - Nature Reviews Neuroscience, 2006 - nature.com
Neuropeptides that are released from dendrites, such as oxytocin and vasopressin, function
as autocrine or paracrine signals at their site of origin, but can also act at distant brain …

Cancer anorexia‐cachexia syndrome: current issues in research and management

A Inui - CA: a cancer journal for clinicians, 2002 - Wiley Online Library
Cachexia is among the most debilitating and life‐threatening aspects of cancer. Associated
with anorexia, fat and muscle tissue wasting, psychological distress, and a lower quality of …

Ghrelin, appetite, and gastric motility: the emerging role of the stomach as an endocrine organ

A Inui, A Asakawa, C Y. Bowers… - The FASEB …, 2004 - Wiley Online Library
Recent progress in the field of energy homeostasis was triggered by the discovery of
adipocyte hormone leptin and revealed a complex regulatory neuroendocrine network. A …

Corticotropin-releasing factor receptors and stress-related alterations of gut motor function

Y Taché, B Bonaz - The Journal of clinical investigation, 2007 - jci.org
Over the past few decades, corticotropin-releasing factor (CRF) signaling pathways have
been shown to be the main coordinators of the endocrine, behavioral, and immune …

The neurocircuitry and receptor subtypes mediating anxiolytic-like effects of neuropeptide Y

A Kask, J Harro, S von Hörsten, JP Redrobe… - Neuroscience & …, 2002 - Elsevier
This review aims to give a brief overview of NPY receptor distribution and physiology in the
brain and summarizes series of studies, test by test and region by region, aimed at …

Genetics of irritable bowel syndrome: shifting gear via biobank-scale studies

M Camilleri, A Zhernakova, I Bozzarelli… - Nature Reviews …, 2022 - nature.com
The pathophysiology of irritable bowel syndrome (IBS) is multifactorial and probably
involves genetic predisposition and the effect of environmental factors. Unlike other …

Hindbrain noradrenergic A2 neurons: diverse roles in autonomic, endocrine, cognitive, and behavioral functions

L Rinaman - American Journal of Physiology-Regulatory …, 2011 - journals.physiology.org
Central noradrenergic (NA) signaling is broadly implicated in behavioral and physiological
processes related to attention, arousal, motivation, learning and memory, and homeostasis …

Neuromedin U and its receptors: structure, function, and physiological roles

PJ Brighton, PG Szekeres, GB Willars - Pharmacological reviews, 2004 - Elsevier
Neuromedin U (NmU) is a structurally highly conserved neuropeptide. It is ubiquitously
distributed, with highest levels found in the gastrointestinal tract and pituitary. Originally …

[HTML][HTML] Anti-inflammatory properties of the μ opioid receptor support its use in the treatment of colon inflammation

D Philippe, L Dubuquoy, H Groux, V Brun… - The Journal of clinical …, 2003 - jci.org
The physiologic role of the μ opioid receptor (MOR) in gut nociception, motility, and secretion
is well established. To evaluate whether MOR may also be involved in controlling gut …

Neuroendocrine control of the gut during stress: corticotropin-releasing factor signaling pathways in the spotlight

A Stengel, Y Taché - Annual review of physiology, 2009 - annualreviews.org
Stress affects the gastrointestinal tract as part of the visceral response. Various stressors
induce similar profiles of gut motor function alterations, including inhibition of gastric …