Edible seaweeds: a potential novel source of bioactive metabolites and nutraceuticals with human health benefits

B Choudhary, OP Chauhan, A Mishra - Frontiers in Marine Science, 2021 - frontiersin.org
There has been an increase in human health concerns, and seaweeds are considered as a
potential functional food which can decrease the risk of many diseases, as they contain …

Clinical and economic burden of adverse drug reactions

J Sultana, P Cutroneo, G Trifirò - Journal of Pharmacology …, 2013 - journals.sagepub.com
Adverse drug reactions (ADRs) are unwanted drug effects that have considerable economic
as well as clinical costs as they often lead to hospital admission, prolongation of hospital …

Systematic reviews: synthesis of best evidence for clinical decisions

DJ Cook, CD Mulrow, RB Haynes - Annals of internal medicine, 1997 - acpjournals.org
Systematic reviews can help practitioners keep abreast of the medical literature by
summarizing large bodies of evidence and hel** to explain differences among studies on …

External validity of randomised controlled trials:“to whom do the results of this trial apply?”

PM Rothwell - The Lancet, 2005 - thelancet.com
In making treatment decisions, doctors and patients must take into account relevant
randomised controlled trials (RCTs) and systematic reviews. Relevance depends on …

Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians evidence-based clinical practice guidelines

J Ansell, J Hirsh, E Hylek, A Jacobson, M Crowther… - Chest, 2008 - Elsevier
This article concerning the pharmacokinetics and pharmacodynamics of vitamin K
antagonists (VKAs) is part of the American College of Chest Physicians Evidence-Based …

Bleeding complications of oral anticoagulant treatment: an inception-cohort, prospective collaborative study (ISCOAT)

G Palareti, N Leali, S Coccheri, M Poggi, C Manotti… - The Lancet, 1996 - thelancet.com
Background Bleeding is the most serious complication of the use of oral anticoagulation in
the prevention and treatment of thromoboembolic complications. We studied the frequency …

The pharmacology and management of the vitamin K antagonists: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy

J Ansell, J Hirsh, L Poller, H Bussey, A Jacobson… - Chest, 2004 - Elsevier
This article concerning the pharmacokinetics and pharmacodynamics of vitamin K
antagonists (VKAs) is part of the Seventh American College of Chest Physicians Conference …

Clinical impact of bleeding in patients taking oral anticoagulant therapy for venous thromboembolism: a meta-analysis

LA Linkins, PT Choi, JD Douketis - Annals of internal medicine, 2003 - acpjournals.org
Background: Clinicians should consider the clinical impact of anticoagulant-related bleeding
when deciding on the duration of anticoagulant therapy in patients with venous …

Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin

BF Gage, C Van Walraven, L Pearce, RG Hart… - Circulation, 2004 - ahajournals.org
Background—The rate of stroke in atrial fibrillation (AF) depends on the presence of
comorbid conditions and the use of antithrombotic therapy. Although adjusted-dose warfarin …

Pharmacogenomics and individualized drug therapy

M Eichelbaum, M Ingelman-Sundberg… - Annu. Rev …, 2006 - annualreviews.org
Pharmacogenetics deals with inherited differences in the response to drugs. The best-
recognized examples are genetic polymorphisms of drug-metabolizing enzymes, which …