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Neonatal sepsis
Neonatal sepsis is the cause of substantial morbidity and mortality. Precise estimates of
neonatal sepsis burden vary by setting. Differing estimates of disease burden have been …
neonatal sepsis burden vary by setting. Differing estimates of disease burden have been …
Infant group B streptococcal disease incidence and serotypes worldwide: systematic review and meta-analyses
L Madrid, AC Seale, M Kohli-Lynch… - Clinical infectious …, 2017 - academic.oup.com
Abstract Background Group B Streptococcus (GBS) remains a leading cause of neonatal
sepsis in high-income contexts, despite declines due to intrapartum antibiotic prophylaxis …
sepsis in high-income contexts, despite declines due to intrapartum antibiotic prophylaxis …
Early-onset neonatal sepsis 2015 to 2017, the rise of Escherichia coli, and the need for novel prevention strategies
BJ Stoll, KM Puopolo, NI Hansen, PJ Sánchez… - JAMA …, 2020 - jamanetwork.com
Importance Early-onset sepsis (EOS) remains a potentially fatal newborn condition. Ongoing
surveillance is critical to optimize prevention and treatment strategies. Objective To describe …
surveillance is critical to optimize prevention and treatment strategies. Objective To describe …
Management of neonates born at≥ 35 0/7 weeks' gestation with suspected or proven early-onset bacterial sepsis
KM Puopolo, WE Benitz, TE Zaoutis, J Cummings… - …, 2018 - publications.aap.org
The incidence of neonatal early-onset sepsis (EOS) has declined substantially over the last
2 decades, primarily because of the implementation of evidence-based intrapartum …
2 decades, primarily because of the implementation of evidence-based intrapartum …
A quantitative, risk-based approach to the management of neonatal early-onset sepsis
MW Kuzniewicz, KM Puopolo, A Fischer… - JAMA …, 2017 - jamanetwork.com
Importance Current algorithms for management of neonatal early-onset sepsis (EOS) result
in medical intervention for large numbers of uninfected infants. We developed multivariable …
in medical intervention for large numbers of uninfected infants. We developed multivariable …
Chorioamnionitis and neonatal outcomes
Chorioamnionitis or intrauterine inflammation is a frequent cause of preterm birth.
Chorioamnionitis can affect almost every organ of the develo** fetus. Multiple microbes …
Chorioamnionitis can affect almost every organ of the develo** fetus. Multiple microbes …
Management of neonates born at≤ 34 6/7 weeks' gestation with suspected or proven early-onset bacterial sepsis
KM Puopolo, WE Benitz, TE Zaoutis, J Cummings… - …, 2018 - publications.aap.org
Early-onset sepsis (EOS) remains a serious and often fatal illness among infants born
preterm, particularly among newborn infants of the lowest gestational age. Currently, most …
preterm, particularly among newborn infants of the lowest gestational age. Currently, most …
Duration of initial empirical antibiotic therapy and outcomes in very low birth weight infants
JY Ting, A Roberts, R Sherlock, C Ojah, Z Cieslak… - …, 2019 - publications.aap.org
BACKGROUND: Overuse of antibiotics can facilitate antibiotic resistance and is associated
with adverse neonatal outcomes. We studied the association between duration of antibiotic …
with adverse neonatal outcomes. We studied the association between duration of antibiotic …
Association of use of the neonatal early-onset sepsis calculator with reduction in antibiotic therapy and safety: a systematic review and meta-analysis
Importance The neonatal early-onset sepsis (EOS) calculator is a clinical risk stratification
tool increasingly used to guide the use of empirical antibiotics for newborns. Evidence on …
tool increasingly used to guide the use of empirical antibiotics for newborns. Evidence on …
Neonatal Sepsis: The Impact of Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae
The convergence of a vulnerable population and a notorious pathogen is devastating, as
seen in the case of sepsis occurring during the first 28 days of life (neonatal period). Sepsis …
seen in the case of sepsis occurring during the first 28 days of life (neonatal period). Sepsis …