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Signaling pathways and therapeutic interventions in gastric cancer
Gastric cancer (GC) ranks fifth in global cancer diagnosis and fourth in cancer-related death.
Despite tremendous progress in diagnosis and therapeutic strategies and significant …
Despite tremendous progress in diagnosis and therapeutic strategies and significant …
Extended lymphadenectomy for gastric cancer in the neoadjuvant era: current status, clinical implications and contentious issues
Despite its decreasing incidence, gastric cancer remains an important global healthcare
problem due to its overall high prevalence and high mortality rate. Since the MAGIC and …
problem due to its overall high prevalence and high mortality rate. Since the MAGIC and …
Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer
X Liu, Y Lu, Y Xu, S Hou, J Huang, B Wang, J Zhao… - Cancer letters, 2019 - Elsevier
Exosomal transfer of oncogenic miRNAs can enhance recipient cell growth, metastasis and
chemoresistance. Currently we found that microRNA-501-5p (miR-501) was overexpressed …
chemoresistance. Currently we found that microRNA-501-5p (miR-501) was overexpressed …
[HTML][HTML] Perioperative treatment in resectable gastric cancer: current perspectives and future directions
A Petrillo, L Pompella, G Tirino, A Pappalardo… - Cancers, 2019 - mdpi.com
Gastric cancer (GC) is the fifth-most common cancer worldwide and an important cause of
cancer-related-death. The growing knowledge of its molecular pathogenesis has shown that …
cancer-related-death. The growing knowledge of its molecular pathogenesis has shown that …
Claudin-6 is a single prognostic marker and functions as a tumor-promoting gene in a subgroup of intestinal type gastric cancer
T Kohmoto, K Masuda, K Shoda, R Takahashi, S Ujiro… - Gastric Cancer, 2020 - Springer
Background We aimed to identify novel tumor-promoting drivers highly expressed in gastric
cancer (GC) that contribute to worsened prognosis in affected patients. Methods Genes …
cancer (GC) that contribute to worsened prognosis in affected patients. Methods Genes …
Immunological aspects of the tumor microenvironment and epithelial-mesenchymal transition in gastric carcinogenesis
Infection with Helicobacter pylori, a Gram-negative, microaerophilic pathogen often results in
gastric cancer in a subset of affected individuals. This explains why H. pylori is the only …
gastric cancer in a subset of affected individuals. This explains why H. pylori is the only …
Histological and mutational profile of diffuse gastric cancer: current knowledge and future challenges
J Garcia‐Pelaez, R Barbosa‐Matos, I Gullo… - Molecular …, 2021 - Wiley Online Library
Gastric cancer (GC) pathogenesis is complex and heterogeneous, reflecting morphological,
molecular and genetic diversity. Diffuse gastric cancer (DGC) and intestinal gastric cancer …
molecular and genetic diversity. Diffuse gastric cancer (DGC) and intestinal gastric cancer …
Exosomal transfer of macrophage-derived miR-223 confers doxorubicin resistance in gastric cancer
H Gao, J Ma, Y Cheng, P Zheng - OncoTargets and therapy, 2020 - Taylor & Francis
Purpose Macrophages are a major component of the tumour microenvironment and play an
important role in chemoresistance of cancer. However, how exosomal microRNAs (miRNAs) …
important role in chemoresistance of cancer. However, how exosomal microRNAs (miRNAs) …
Multimodality treatment for localized gastric cancer: state of the art and new insights
A Petrillo, EC Smyth - Current Opinion in Oncology, 2020 - journals.lww.com
Multimodality treatment represents the standard of care for resectable gastric cancer.
Perioperative chemotherapy with FLOT is the standard treatment in western countries; in …
Perioperative chemotherapy with FLOT is the standard treatment in western countries; in …
Curcumin micelles suppress gastric tumor cell growth by upregulating ROS generation, disrupting redox equilibrium and affecting mitochondrial bioenergetics
X Lin, L Wang, L Zhao, Z Zhu, TZ Chen, S Chen… - Food & function, 2020 - pubs.rsc.org
Gastric cancer is the fourth most common cancer and the second most frequent cause of
cancer death worldwide. Chemotherapy is an important treatment. However, traditional …
cancer death worldwide. Chemotherapy is an important treatment. However, traditional …