Optimizing methods and dodging pitfalls in microbiome research
Research on the human microbiome has yielded numerous insights into health and disease,
but also has resulted in a wealth of experimental artifacts. Here, we present suggestions for …
but also has resulted in a wealth of experimental artifacts. Here, we present suggestions for …
[PDF][PDF] Practical considerations for large-scale gut microbiome studies
D Vandeputte, RY Tito, R Vanleeuwen… - FEMS microbiology …, 2017 - academic.oup.com
First insights on the human gut microbiome have been gained from medium-sized, cross-
sectional studies. However, given the modest portion of explained variance of currently …
sectional studies. However, given the modest portion of explained variance of currently …
Gut microbiome heritability is nearly universal but environmentally contingent
Relatives have more similar gut microbiomes than nonrelatives, but the degree to which this
similarity results from shared genotypes versus shared environments has been …
similarity results from shared genotypes versus shared environments has been …
Seasonal shifts in the gut microbiome indicate plastic responses to diet in wild geladas
Background Adaptive shifts in gut microbiome composition are one route by which animals
adapt to seasonal changes in food availability and diet. However, outside of dietary shifts …
adapt to seasonal changes in food availability and diet. However, outside of dietary shifts …
Climate change drives loss of bacterial gut mutualists at the expense of host survival in wild meerkats
Climate change and climate‐driven increases in infectious disease threaten wildlife
populations globally. Gut microbial responses are predicted to either buffer or exacerbate …
populations globally. Gut microbial responses are predicted to either buffer or exacerbate …
Impact of preservation method and 16S rRNA hypervariable region on gut microbiota profiling
Proper preservation of stool samples to minimize microbial community shifts and inactivate
infectious agents is important for self-collected specimens requiring shipment to laboratories …
infectious agents is important for self-collected specimens requiring shipment to laboratories …
Generating amplicon reads for microbial community assessment with next‐generation sequencing
M Gołębiewski, A Tretyn - Journal of Applied Microbiology, 2020 - academic.oup.com
Marker gene amplicon sequencing is often preferred over whole genome sequencing for
microbial community characterization, due to its lower cost while still enabling assessment of …
microbial community characterization, due to its lower cost while still enabling assessment of …
Longitudinal gut microbiome dynamics in relation to age and senescence in a wild animal population
In humans, gut microbiome (GM) differences are often correlated with, and sometimes
causally implicated in, ageing. However, it is unclear how these findings translate in wild …
causally implicated in, ageing. However, it is unclear how these findings translate in wild …
Altitudinal variation of the gut microbiota in wild house mice
The maintenance of oxygen homeostasis in the gut is critical for the maintenance of a
healthy gut microbiota. However, few studies have explored how the concentration of …
healthy gut microbiota. However, few studies have explored how the concentration of …
Standard sample storage conditions have an impact on inferred microbiome composition and antimicrobial resistance patterns
Storage of biological specimens is crucial in the life and medical sciences. Storage
conditions for samples can be different for a number of reasons, and it is unclear what effect …
conditions for samples can be different for a number of reasons, and it is unclear what effect …