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[HTML][HTML] A comprehensive review of key factors affecting the efficacy of antibody drug conjugate
A Samantasinghar, NP Sunildutt, F Ahmed… - Biomedicine & …, 2023 - Elsevier
Abstract Antibody Drug Conjugate (ADC) is an emerging technology to overcome the
limitations of chemotherapy by selectively targeting the cancer cells. ADC binds with an …
limitations of chemotherapy by selectively targeting the cancer cells. ADC binds with an …
[HTML][HTML] A comprehensive review of artificial intelligence and network based approaches to drug repurposing in Covid-19
Conventional drug discovery and development is tedious and time-taking process; because
of which it has failed to keep the required pace to mitigate threats and cater demands of viral …
of which it has failed to keep the required pace to mitigate threats and cater demands of viral …
Drug repurposing for viral cancers: A paradigm of machine learning, deep learning, and virtual screening‐based approaches
Cancer management is major concern of health organizations and viral cancers account for
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …
[HTML][HTML] A systematic review of computational approaches to understand cancer biology for informed drug repurposing
F Ahmed, A Samantasinghar, AM Soomro, S Kim… - Journal of Biomedical …, 2023 - Elsevier
Cancer is the second leading cause of death globally, trailing only heart disease. In the
United States alone, 1.9 million new cancer cases and 609,360 deaths were recorded for …
United States alone, 1.9 million new cancer cases and 609,360 deaths were recorded for …
Artificial intelligence-assisted repurposing of lubiprostone alleviates tubulointerstitial fibrosis
Tubulointerstitial fibrosis (TIF) is the most prominent cause which leads to chronic kidney
disease (CKD) and end-stage renal failure. Despite extensive research, there have been …
disease (CKD) and end-stage renal failure. Despite extensive research, there have been …
Revolutionizing drug development: harnessing the potential of organ-on-chip technology for disease modeling and drug discovery
N Sunildutt, P Parihar… - Frontiers in …, 2023 - frontiersin.org
The inefficiency of existing animal models to precisely predict human pharmacological
effects is the root reason for drug development failure. Microphysiological system/organ-on …
effects is the root reason for drug development failure. Microphysiological system/organ-on …
A review of SARS-CoV-2 drug repurposing: Databases and machine learning models
The emergence of Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2)
posed a serious worldwide threat and emphasized the urgency to find efficient solutions to …
posed a serious worldwide threat and emphasized the urgency to find efficient solutions to …
Navigating with chemometrics and machine learning in chemistry
PB Joshi - Artificial Intelligence Review, 2023 - Springer
Chemometrics and machine learning are artificial intelligence-based methods stirring a
transformative change in chemistry. Organic synthesis, drug discovery and analytical …
transformative change in chemistry. Organic synthesis, drug discovery and analytical …
Improved intelligent methods for power transformer fault diagnosis based on tree ensemble learning and multiple feature vector analysis
This paper discusses the impact of the feature input vector on the performance of dissolved
gas analysis-based intelligent power transformer fault diagnosis methods. For this purpose …
gas analysis-based intelligent power transformer fault diagnosis methods. For this purpose …
[HTML][HTML] Drug repurposing in psoriasis, performed by reversal of disease-associated gene expression profiles
Psoriasis is a skin disease which results in scales on the skin caused by flaky patches.
Psoriasis is triggered by various conditions such as drug reactions, trauma, and skin …
Psoriasis is triggered by various conditions such as drug reactions, trauma, and skin …