Although organic compounds account for more than 99% of currently approved clinical
drugs, the established clinical use of cisplatin in cancer or auranofin in rheumatoid arthritis …

Dimerization is a promising strategy to develop novel drug candidates that could extend the
biological spectrum, enhance the activity, overcome drug resistance, as well as improve …

A series of diethylene glycol tethered bis‐istain derivatives 4 a‐o were designed,
synthesized and screened for their biological activities in this paper. Eight bis‐isatin …

Thanks to its pharmaceutical properties, the Schiff group of isatin has recently had a wide
range of uses. In this study, seven new Schiff bases of isatin and its derivatives were …

In the present study, design, synthesis, characterization, and investigation of antioxidant
properties of novel asymmetric bis-isatin derivatives (1-8) containing urea/thiourea moiety …

Many bis-isatins and isatins with hydrazide extension were reported to have a potential anti-
proliferative effects against different cancer cell lines and cancer targets. In this study, four …

A new series of indolylhydrazones (6) and indole-based 4-thiazolidinones (7, 8) have been
designed, synthesized and screened for in vitro antitubercular activity against …

New solvated Mo (VI) complexes were isolated from the reaction of [MoO2 (acac) 2] with
asymmetric isatin bisthiocarbohydrazone ligands. The ligands were obtained from the …

A simple, straightforward and efficient method has been developed for the synthesis of (E)-3-
(arylimino) indolin-2-one derivatives and (E)-2-((4-methoxyphenyl) imino)-acenaphthylen-1 …

A series of new β-isatin aldehyde-N, N′-thiocarbohydrazone, bis-β-isatin
thiocarbohydrazones, bis-β-isatin carbohydrazones was synthesized by condensation of 5 …