[HTML][HTML] Neutron reflection and scattering in characterising peptide assemblies
Self-assemblies of de novo designed short peptides at interface and in bulk solution provide
potential platforms for develo** applications in many medical and technological areas …
potential platforms for develo** applications in many medical and technological areas …
[HTML][HTML] Exploring proteins at soft interfaces and in thin liquid films–From classical methods to advanced applications of reflectometry
The history of the topic of proteins at soft interfaces dates back to the 19th century, and until
the present day, it has continuously attracted great scientific interest. A multitude of …
the present day, it has continuously attracted great scientific interest. A multitude of …
Biophysical determinants for the viscosity of concentrated monoclonal antibody solutions
Monoclonal antibodies (mAbs) are particularly relevant for therapeutics due to their high
specificity and versatility, and mAb-based drugs are hence used to treat numerous diseases …
specificity and versatility, and mAb-based drugs are hence used to treat numerous diseases …
Interfacial Pressure and Viscoelasticity of Antibodies and Their Correlation to Long-Term Stability in Formulation
KG Pham, BR Thompson, T Wang… - The Journal of …, 2023 - ACS Publications
Monoclonal antibodies (mAbs) form viscoelastic gel-like layers at the air–water interface due
to their amphiphilic nature, and this same protein characteristic can lead to undesired …
to their amphiphilic nature, and this same protein characteristic can lead to undesired …
pH-Dependent Conformational Plasticity of Monoclonal Antibodies at the SiO2/Water Interface: Insights from Neutron Reflectivity and Molecular Dynamics
Investigating the molecular conformations of monoclonal antibodies (mAbs) adsorbed at the
solid/liquid interface is crucial for understanding mAb solution stability and advancing the …
solid/liquid interface is crucial for understanding mAb solution stability and advancing the …