The multifaceted anti-cancer properties of colchicine make it a promising candidate for tumor
treatment. However, its application has been limited by poor solubility, low bioavailability …

Phytochemical study of Chiliadenus montanus aerial parts afforded six compounds;
Intermedeol (1), 5α-hydroperoxy-β-eudesmol (2), 5, 7-dihydroxy-3, 3', 4'-trimethoxyflavone …

In this study, a series of 4-[(quinolin-4-yl) amino] benzamide derivatives as the novel anti-
influenza agents were designed and synthesized. Cytotoxicity assay, cytopathic effect assay …

The pursuit for effective strategies inhibiting the amyloidogenic process in
neurodegenerative disorders, such as Alzheimer's disease (AD), remains one of the main …

The cardinal role of microtubules in cell mitosis makes them interesting drug targets for
many pharmacological treatments, including those against cancer. Moreover, different …

Colchicine, a pseudoalkaloid isolated from Colchicum autumnale, has been identified as a
potent anticancer agent because of its strong antimitotic activity. It was shown that colchicine …

Colchicine is a plant alkaloid with a broad spectrum of biological and pharmacological
properties. It has found application as an anti-inflammatory agent and also shows anticancer …

Colchicine is an active pharmaceutical ingredient widely used for treating gout, pericarditis,
and familial Mediterranean fever with high antimitotic activity. The photoisomerization of …

Taste perception is a complex and multi-layered process which involves several
components from the molecular level up to subcellular, cellular, and tissue levels. At the …

The main objective of this work is to provide a topical formulation of a novel thiocolchicoside
derivative drug to treat gout inflammation. The drug has been tested in cell-based assays …