Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of
cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in …

We discuss the anatomy, physiology, and pathophysiology of epicardial adipose tissue and
its relationship to coronary atherosclerosis. Epicardial fat stores triglyceride to supply free …

Background—Inflammation in adipose tissue has been implicated in vascular dysfunction,
but the local mechanisms by which this occurs are unknown. Methods and Results—Small …

Cigarette smoking during pregnancy is associated with numerous obstetrical, fetal, and
developmental complications, as well as an increased risk of adverse health consequences …

Lipedema is a chronic progressive disease characterized by abnormal fat distribution
resulting in disproportionate, painful limbs. It almost exclusively affects women, leading to …

Endothelial dysfunction comprises a number of functional alterations in the vascular
endothelium that are associated with diabetes and cardiovascular disease, including …

Aim: Adipokines are protein products of adipose tissue with paracrine and endocrine
actions, which have been implicated in the pathogenesis of cardiovascular disease. Locally …

Omentin is a recently identified adipose tissue-derived cytokine and is implicated in obesity-
related cardiovascular disorders. In the present study, we tested the hypothesis that omentin …

For more than a century, hydrogen sulfide (H2S) has been regarded as a toxic gas. This
review surveys the growing recognition of the role of H2S as an endogenous signaling …