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Pharmacogenetic research activity in Central America and the Caribbean: a systematic review
Aim: The present review was aimed at analyzing the pharmacogenetic scientific activity in
Central America and the Caribbean. Materials & methods: A literature search for …
Central America and the Caribbean. Materials & methods: A literature search for …
Tyrosine kinase inhibitor sensitive PDGFRΑ mutations in GIST: Two cases and review of the literature
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal malignancies of the
gastrointestinal tract. Most GISTs harbor a c-KIT (80%) or a PDGFRα (10%) mutation that …
gastrointestinal tract. Most GISTs harbor a c-KIT (80%) or a PDGFRα (10%) mutation that …
Molecular analysis of the KIT gene in gastrointestinal stromal tumors with novel mutations
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the
gastrointestinal tract. KIT gene mutations have great importance for GISTs. This study …
gastrointestinal tract. KIT gene mutations have great importance for GISTs. This study …
Gastrointestinal stromal tumor: genotype frequency and prognostic relevance
Background: Genoty** has an important role in the prognosis and prediction of response
to tyrosine kinase inhibitor therapy. KIT exon 11 deletions serve as an adverse prognostic …
to tyrosine kinase inhibitor therapy. KIT exon 11 deletions serve as an adverse prognostic …
Somatic mutational spectrum analysis in a prospective series of 104 gastrointestinal stromal tumors
D Guenat, O Deroo, S Magnin… - Oncology …, 2017 - spandidos-publications.com
Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors distinguished by driver
mutations in proto-oncogenes KIT or PDGFRA in 85-90% of cases. These mutations have …
mutations in proto-oncogenes KIT or PDGFRA in 85-90% of cases. These mutations have …
Analysis of clinicopathologic features and gene mutations in gastrointestinal stromal tumor: a series of 58 patients
H Cheng, T Qiu, SS Shi - International Journal of Clinical and …, 2021 - pmc.ncbi.nlm.nih.gov
Background: In gastrointestinal stromal tumor (GIST), mutually exclusive gain-of-function
mutations of c-kit and PDGFRα are associated with different mutation-dependent clinical …
mutations of c-kit and PDGFRα are associated with different mutation-dependent clinical …
Frequency of KIT mutation in gastrointestinal stromal tumors according to histologic and immunohistochemical findings, the first report from Iran
Background Gastrointestinal stromal tumor (GIST) is the most common mesenchymal
neoplasm of the gastrointestinal tract. They are believed to originate from the interstitial cells …
neoplasm of the gastrointestinal tract. They are believed to originate from the interstitial cells …
Molecular and immunohistochemical study of platelet derived growth factor receptor alpha in KIT negative gastrointestinal stromal tumors; the first report from Iran
BACKGROUND Gastrointestinal stromal tumors (GISTs) are potentially malignant tumors;
however their behavior and response to treatment is dependent on the type of mutation and …
however their behavior and response to treatment is dependent on the type of mutation and …
[PDF][PDF] The frequencies of c-kit proto-oncogene (KIT) mutations in gastrointestinal stromal tumours: a population based study from Aegean Region of Turkey
G Çalıbaşı - Türk Biyokimya Dergisi [Turkish Journal of …, 2013 - academia.edu
Objectives: The c-kit proto-oncogene (KIT) exon 9, 11, 13 and 17 activation mutations are
associated with clinical behaviour in gastrointestinal stromal tumors with highly variable …
associated with clinical behaviour in gastrointestinal stromal tumors with highly variable …
Clinicopathological Features and Gene Mutation Analysis of Gastrointestinal Stromal Tumors: A Series of 58 Patients
T Qiu, S Shi - 2021 - researchsquare.com
[Background] In gastrointestinal stromal tumors (GISTs), mutually exclusive gain-of-function
mutations of KIT and PDGFRA are associated with different mutation-dependent clinical …
mutations of KIT and PDGFRA are associated with different mutation-dependent clinical …