Epilepsy surgery in children and adults

P Ryvlin, JH Cross, S Rheims - The Lancet Neurology, 2014 - thelancet.com
Epilepsy surgery is the most effective way to control seizures in patients with drug-resistant
focal epilepsy, often leading to improvements in cognition, behaviour, and quality of life …

Surgical treatment for epilepsy: the potential gap between evidence and practice

N Jetté, JW Sander, MR Keezer - The Lancet Neurology, 2016 - thelancet.com
Findings from randomised controlled trials, along with more than 100 case series and
observational studies, support the efficacy and safety of resective surgery and, more …

Epilepsy: new advances

SL Moshé, E Perucca, P Ryvlin, T Tomson - The Lancet, 2015 - thelancet.com
Epilepsy affects 65 million people worldwide and entails a major burden in seizure-related
disability, mortality, comorbidities, stigma, and costs. In the past decade, important advances …

What can we do for people with drug-resistant epilepsy? The 2016 Wartenberg Lecture

J Engel Jr - Neurology, 2016 - AAN Enterprises
Treatment goals for epilepsy are no seizures, no side effects, as soon as possible, but these
goals are too often unmet. Approximately 1 million people in the United States continue to …

Referral to evaluation for epilepsy surgery: reluctance by epileptologists and patients

M Steinbrenner, AB Kowski, M Holtkamp - Epilepsia, 2019 - Wiley Online Library
Objective Despite the obvious advantages of resective surgery in patients with drug‐
resistant focal epilepsy, namely high probability of seizure freedom, decreased mortality …

Psychiatric and behavioral comorbidities in epilepsy: a critical reappraisal

AT Berg, HH Altalib, O Devinsky - Epilepsia, 2017 - Wiley Online Library
Psychiatric and behavioral disorders are important aspects of epilepsy and have received
increasing attention in the last several years. The literature upon which most of the field …

Prospective validation of a machine learning model that uses provider notes to identify candidates for resective epilepsy surgery

BD Wissel, HM Greiner, TA Glauser… - …, 2020 - Wiley Online Library
Objective Delay to resective epilepsy surgery results in avoidable disease burden and
increased risk of mortality. The objective was to prospectively validate a natural language …

Cost-effectiveness of surgery for drug-resistant temporal lobe epilepsy in the US

SR Sheikh, MW Kattan, M Steinmetz, ME Singer… - Neurology, 2020 - AAN Enterprises
Objective Surgery is an effective but costly treatment for many patients with drug-resistant
temporal lobe epilepsy (DR-TLE). We aim to evaluate whether, in the United States, surgery …

Identification and treatment of drug-resistant epilepsy

JY Yoo, F Panov - CONTINUUM: Lifelong Learning in Neurology, 2019 - journals.lww.com
PURPOSE OF REVIEW Drug-resistant epilepsy is a potentially life-threatening condition
affecting one-third of people living with epilepsy. Despite existing evidence of improved …

Methodological issues in predicting pediatric epilepsy surgery candidates through natural language processing and machine learning

KB Cohen, B Glass, HM Greiner… - Biomedical …, 2016 - journals.sagepub.com
Objective: We describe the development and evaluation of a system that uses machine
learning and natural language processing techniques to identify potential candidates for …