Cognition can be conceptualized as a set of algorithmic control functions whose real-time
deployment determines how an organism stores and uses information to guide thought and …

Historically, the thalamus has been viewed as little more than a relay, simply transferring
information to key players of the cast, the cortex and hippocampus, without providing any …

Although interactions between the thalamus and cortex are critical for cognitive function,,,
the exact contribution of the thalamus to these interactions remains unclear. Recent studies …

The mediodorsal thalamus (MD) shares reciprocal connectivity with the prefrontal cortex
(PFC), and decreased MD–PFC connectivity is observed in schizophrenia patients. Patients …

The ability to adapt to dynamic environments requires tracking multiple signals with variable
sensory salience and fluctuating behavioral relevance. This complex process requires …

Fear extinction is a form of inhibitory learning that suppresses the expression of aversive
memories and plays a key role in the recovery of anxiety and trauma-related disorders …

Executive control, the ability to organize thoughts and action plans in real time, is a defining
feature of higher cognition. Classical theories have emphasized cortical contributions to this …

The mediodorsal thalamus (MD) and anterior thalamic nuclei (ATN) are two adjacent brain
nodes that support our ability to make decisions, learn, update information, form and retrieve …

Predictive learning can engage a selective form of cognitive control that biases choice
between actions based on information about future outcomes that the learning provides …

Interactions across frontal cortex are critical for cognition. Animal studies suggest a role for
mediodorsal thalamus (MD) in these interactions, but the computations performed and direct …