A neurodevelopment approach for a transitional model of early onset schizophrenia
In the last decades, the conceptualization of schizophrenia has dramatically changed,
moving from a neurodegenerative process occurring in early adult life to a …
moving from a neurodegenerative process occurring in early adult life to a …
The genetic basis of onset age in schizophrenia: evidence and models
Schizophrenia is a heritable neurocognitive disorder affecting about 1% of the population,
and usually has an onset age at around 21–25 in males and 25–30 in females. Recent …
and usually has an onset age at around 21–25 in males and 25–30 in females. Recent …
Study of Early Onset Schizophrenia: Associations of GRIN2A and GRIN2B Polymorphisms
EG Poltavskaya, OY Fedorenko, EG Kornetova… - Life, 2021 - mdpi.com
Background: Schizophrenia is a complex mental disorder with a high heritability.
Dysfunction of the N-methyl-D-aspartate (NMDA)-type glutamate receptors may be involved …
Dysfunction of the N-methyl-D-aspartate (NMDA)-type glutamate receptors may be involved …
Cannabis and psychosis
ML West, S Sharif - Psychiatric Clinics, 2023 - psych.theclinics.com
Psychosis is a cluster of symptoms that involve difficulties knowing what is real and what is
not real. As with any mental health experience, psychosis can be seen as a spectrum of …
not real. As with any mental health experience, psychosis can be seen as a spectrum of …
Prodromal symptoms and the duration of untreated psychosis in first episode of psychosis patients: what differences are there between early vs. adult onset and …
To assess the role of age (early onset psychosis-EOP< 18 years vs. adult onset psychosis-
AOP) and diagnosis (schizophrenia spectrum disorders-SSD vs. bipolar disorders-BD) on …
AOP) and diagnosis (schizophrenia spectrum disorders-SSD vs. bipolar disorders-BD) on …
Clinical features and comorbidity in very early-onset schizophrenia: a systematic review
M Di Luzio, M Pontillo, M Villa, AG Attardi… - Frontiers in …, 2023 - frontiersin.org
Background Very early-onset schizophrenia (VEOS) is a form of schizophrenia that
manifests before the age of 13 years and is characterized by the presence of positive …
manifests before the age of 13 years and is characterized by the presence of positive …
[HTML][HTML] Composite immune marker scores associated with severe mental disorders and illness course
MBEG Ormerod, T Ueland, MCF Werner, G Hjell… - Brain, Behavior, & …, 2022 - Elsevier
Background Low-grade inflammation has been implicated in the pathophysiology of severe
mental disorders (SMDs) and a link between immune activation and clinical characteristics …
mental disorders (SMDs) and a link between immune activation and clinical characteristics …
Association of serum interleukin-6 with negative symptoms in stable early-onset schizophrenia
P Chen, HD Yang, JJ Wang, ZH Zhu… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND Accumulating evidence suggests that the inflammatory cytokine interleukin-
6 (IL-6) contributes to the pathophysiology of psychiatric disorders. However, there was no …
6 (IL-6) contributes to the pathophysiology of psychiatric disorders. However, there was no …
Positive psychotic symptoms in childhood and adolescence
Based on the assumption of a universal neurodevelopmental model of psychosis, especially
of the schizophrenia spectrum, the diagnosis (and treatment) of psychosis in minors …
of the schizophrenia spectrum, the diagnosis (and treatment) of psychosis in minors …
Challenges and opportunities in the diagnosis and treatment of early-onset psychosis: a case series from the youth affective disorders clinic in Stockholm, Sweden
Early-onset psychosis is linked to adverse long-term outcomes, recurrent disease course,
and prolonged periods of untreated illness; thus highlighting the urgency of improving early …
and prolonged periods of untreated illness; thus highlighting the urgency of improving early …