Thermally activated delayed fluorescence material: An emerging class of metal‐free luminophores for biomedical applications

F Fang, L Zhu, M Li, Y Song, M Sun, D Zhao… - Advanced …, 2021 - Wiley Online Library
The development of simple, efficient, and biocompatible organic luminescent molecules is of
great significance to the clinical transformation of biomaterials. In recent years, purely …

[HTML][HTML] Carrier-free nanodrugs with efficient drug delivery and release for cancer therapy: From intrinsic physicochemical properties to external modification

H Mei, S Cai, D Huang, H Gao, J Cao, B He - Bioactive materials, 2022 - Elsevier
The considerable development of carrier-free nanodrugs has been achieved due to their
high drug-loading capability, simple preparation method, and offering “all-in-one” functional …

Continuous spatiotemporal therapy of a full-API nanodrug via multi-step tandem endogenous biosynthesis

F Fang, S Wang, Y Song, M Sun, WC Chen… - Nature …, 2023 - nature.com
Nanomedicine holds great promise to enhance cancer therapy. However, low active
pharmaceutical ingredient (API) loading content, unpredictable drug release, and potential …

[HTML][HTML] Pure drug nano-assemblies: A facile carrier-free nanoplatform for efficient cancer therapy

S Fu, G Li, W Zang, X Zhou, K Shi, Y Zhai - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Nanoparticulate drug delivery systems (Nano-DDSs) have emerged as possible solution to
the obstacles of anticancer drug delivery. However, the clinical outcomes and translation are …

Cu-MOF chemodynamic nanoplatform via modulating glutathione and H2O2 in tumor microenvironment for amplified cancer therapy

H Tian, M Zhang, G **, Y Jiang, Y Luan - Journal of Colloid and Interface …, 2021 - Elsevier
Chemodynamic therapy (CDT) utilizes Fenton catalysts to convert intracellular hydrogen
peroxide (H 2 O 2) into cytotoxic hydroxyl radical (OH∙) for tumor therapy, but endogenous H …

High drug-loading nanomedicines: progress, current status, and prospects

S Shen, Y Wu, Y Liu, D Wu - International journal of nanomedicine, 2017 - Taylor & Francis
Drug molecules transformed into nanoparticles or endowed with nanostructures with or
without the aid of carrier materials are referred to as “nanomedicines” and can overcome …

Advances and perspectives in carrier-free nanodrugs for cancer chemo-monotherapy and combination therapy

L Huang, S Zhao, F Fang, T Xu, M Lan, J Zhang - Biomaterials, 2021 - Elsevier
Nanocarrier-based drug delivery systems hold impressive promise for biomedical
application because of their excellent water dispersibility, prolonged blood circulation time …

Drug self-delivery systems for cancer therapy

SY Qin, AQ Zhang, SX Cheng, L Rong, XZ Zhang - Biomaterials, 2017 - Elsevier
Carrier-assistant drug delivery systems (DDSs) have been rapidly established for cancer
therapy and great strides have been made in recent years. However, further development of …

Carrier-free nanomedicines for cancer treatment

LH Liu, XZ Zhang - Progress in Materials Science, 2022 - Elsevier
The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

Recent advances in photonanomedicines for enhanced cancer photodynamic therapy

JJ Hu, Q Lei, XZ Zhang - Progress in Materials Science, 2020 - Elsevier
Nowadays, photodynamic therapy (PDT) that employs photosensitizers (PSs) to generate
cytotoxic species under light irradiation for selective destruction of neoplastic lesions has …