Hypertrophic scarring (HTS) is an aberrant form of wound healing that is associated with
excessive deposition of extracellular matrix and connective tissue at the site of injury. In this …

Numerous therapeutic strategies have been described for prevention and reduction of
hypertrophic scars and keloids, but none of the treatments is effective in all patients. No …

Skin wound healing is essential to health and survival. Consequently, high amounts of
research effort have been put into investigating the cellular and molecular components …

Keloids are pathological scars that grow over time and extend beyond the initial site of injury
after impaired wound healing. These scars frequently recur and rarely regress. They are …

The successful treatment of keloids is a great challenge in the plastic surgery field. Activating
transcription factor 3 (ATF3) is discovered as an adaptive responsive gene, which plays a …

Keloid scars, characterized by abnormal fibroproliferation and excessive extracellular matrix
(ECM) production that extends beyond the original wound, often cause pruritus, pain, and …

Background Triamcinolone acetonide (TAC) is widely used for hypertrophic scars and
keloids; however, TAC has variable efficacy and safety in different individuals. Purpose To …

Objectives At present, there are many therapies for treating keloids and hypertrophic scars,
but there is still a lack of treatments that are relatively balanced in efficacy and safety. The …

Burns are traumatic tissue injuries accompanied by various physiological and psychological
morbidities. 1–3 Scar is the most apparent pathognomonic characteristic of burn injury and …

Hypertrophic scars (HTS) are elevated scars which occur due to abnormalities in wound
healing after injury and may be associated with pain, pruritus and functional impairment …