Resveratrol and neuroprotection: an insight into prospective therapeutic approaches against Alzheimer's disease from bench to bedside

F Islam, MH Nafady, MR Islam, S Saha, S Rashid… - Molecular …, 2022 - Springer
Alzheimer's disease (AD) is the most common cause of dementia and cognitive impairment;
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …

Why is longevity still a scientific mystery? Sirtuins—past, present and future

P Ziętara, M Dziewięcka, M Augustyniak - International Journal of …, 2022 - mdpi.com
The sirtuin system consists of seven highly conserved regulatory enzymes responsible for
metabolism, antioxidant protection, and cell cycle regulation. The great interest in sirtuins is …

Recent advances in health benefits of stilbenoids

YC Koh, CT Ho, MH Pan - Journal of agricultural and food …, 2021 - ACS Publications
Biological targeting or molecular targeting is the main strategy in drug development and
disease prevention. However, the problem of “off-targets” cannot be neglected. Naturally …

Resveratrol-loaded nanocarriers: Characteristics, sources, health effects, recent delivery systems, and their food and biomedical applications

M Rostami, N Beheshtizadeh, EL Mazaheri, G Mirzaei… - Food Bioscience, 2024 - Elsevier
Abstract Resveratrol (3, 5, 4′-trihydroxystilbene, RES) is a polyphenolic phytoalexin widely
studied in the recent years due to its known several biological activities. In spite of the …

Nanomedicine as an emerging technology to foster application of essential oils to fight cancer

K AbouAitah, W Lojkowski - Pharmaceuticals, 2022 - mdpi.com
Natural prodrugs extracted from plants are increasingly used in many sectors, including the
pharmaceutical, cosmetic, and food industries. Among these prodrugs, essential oils (EOs) …

Intranasal in situ gelling liquid crystal for delivery of resveratrol ameliorates memory and neuroinflammation in Alzheimer's disease

B Fonseca-Santos, CA Cazarin, PB da Silva… - … , Biology and Medicine, 2023 - Elsevier
Alzheimer's disease (AD) is an illness that affects people aged 65 or older and affects
around 6.5 million in the United States. Resveratrol is a chemical obtained from natural …

Delivery of natural agents by means of mesoporous silica nanospheres as a promising anticancer strategy

K AbouAitah, W Lojkowski - Pharmaceutics, 2021 - mdpi.com
Natural prodrugs derived from different natural origins (eg, medicinal plants, microbes,
animals) have a long history in traditional medicine. They exhibit a broad range of …

Therapeutic effects of natural products on cervical cancer: based on inflammatory pathways

ZW Zhou, HZ Long, SG Xu, FJ Li, Y Cheng… - Frontiers in …, 2022 - frontiersin.org
Inflammation is a protective response of the body to an irritant. When an inflammatory
response occurs, immune cells are recruited to the injury, eliminating the irritation. The …

Resveratrol has an overall neuroprotective role in ischemic stroke: a meta-analysis in rodents

J Liu, J He, Y Huang, Z Hu - Frontiers in Pharmacology, 2021 - frontiersin.org
Background: Resveratrol, a natural polyphenolic phytoalexin, is broadly presented in dietary
sources. Previous research has suggested its potential neuroprotective effects on ischemic …

Resveratrol-based compounds and neurodegeneration: Recent insight in multitarget therapy

M Fantacuzzi, R Amoroso, S Carradori… - European Journal of …, 2022 - Elsevier
Neurodegenerative diseases (NDs) are characterized by gradual and progressive loss of
selectively vulnerable populations of neurons, including death of neurons in different …