Epithelial ovarian cancer generally presents at an advanced stage and is the most common
cause of gynaecological cancer death. Treatment requires expert multidisciplinary care …

Aim: Ovarian cancer is one of the most common gynecologic cancers that has the highest
mortality rate. Considering the fact that knowledge on the incidence, mortality of ovarian …

PURPOSE To provide recommendations on genetic and tumor testing for women diagnosed
with epithelial ovarian cancer based on available evidence and expert consensus …

Purpose Multiple-gene, next-generation sequencing panels are increasingly used to assess
hereditary cancer risks of patients with diverse personal and family cancer histories. The …

Simple Summary Ovarian cancer (OC) represents the fifth leading cause of cancer-related
deaths among women. In the advanced disease setting, OC recurrence after chemotherapy …

Simple Summary Microsatellite instability (MSI) is a hallmark of Lynch syndrome (LS)-related
tumors but is not specific, as most of MSI/mismatch repair-deficient (dMMR) tumors are …

Ovarian clear cell carcinoma (OCCC) is distinctive from other histological types of epithelial
ovarian cancer, with genetic/epigenetic alterations, a specific immune-related molecular …

Background Genetic testing (GT) for hereditary cancer predisposition is traditionally
performed on selected genes based on established guidelines for each cancer type …

Ovarian cancer is a frequent malignancy that affects a large percentage of women.
Endometriosis is a chronic condition, where there is a production of benign lesions were …

Mismatch repair deficiency (MMRD) is involved in the initiation of both hereditary and
sporadic tumors. MMRD has been extensively studied in colorectal cancer and endometrial …