The plastic brain: neurotoxicity of micro-and nanoplastics

M Prüst, J Meijer, RHS Westerink - Particle and fibre toxicology, 2020 - Springer
Given the global abundance and environmental persistence, exposure of humans and
(aquatic) animals to micro-and nanoplastics is unavoidable. Current evidence indicates that …

[HTML][HTML] Toxic chemicals and persistent organic pollutants associated with micro-and nanoplastics pollution

CO Okoye, CI Addey, O Oderinde, JO Okoro… - Chemical Engineering …, 2022 - Elsevier
The prevalence of micro and nanoplastics (MNPs) across the various environments and
their negative impact on ecosystems have become a serious global threat and are currently …

Polystyrene nanoplastics penetrate across the blood-brain barrier and induce activation of microglia in the brain of mice

S Shan, Y Zhang, H Zhao, T Zeng, X Zhao - Chemosphere, 2022 - Elsevier
Microplastics (MPs) have been well demonstrated as potential threats to the ecosystem,
whereas the neurotoxicity of MPs in mammals remains to be elucidated. The current study …

Anionic nanoplastic contaminants promote Parkinson's disease–associated α-synuclein aggregation

Z Liu, A Sokratian, AM Duda, E Xu, C Stanhope… - Science …, 2023 - science.org
Recent studies have identified increasing levels of nanoplastic pollution in the environment.
Here, we find that anionic nanoplastic contaminants potently precipitate the formation and …

Brain single-nucleus transcriptomics highlights that polystyrene nanoplastics potentially induce Parkinson's disease-like neurodegeneration by causing energy …

B Liang, Y Huang, Y Zhong, Z Li, R Ye, B Wang… - Journal of Hazardous …, 2022 - Elsevier
With the prevalence of nanoplastics in daily life, human exposure is inevitable. However,
whether and how nanoplastics cause neurotoxicity in humans remains obscure. Herein, we …

[HTML][HTML] Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing

U Marx, TB Andersson, A Bahinski, M Beilmann… - Altex, 2016 - ncbi.nlm.nih.gov
The recent advent of microphysiological systems–microfluidic biomimetic devices that aspire
to emulate the biology of human tissues, organs and circulation in vitro–is envisaged to …

[HTML][HTML] Unraveling the potential human health risks from used disposable face mask-derived micro/nanoplastics during the COVID-19 pandemic scenario: A critical …

M Li, Z Hou, R Meng, S Hao, B Wang - Environment International, 2022 - Elsevier
With the global spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2),
disposable face masks (DFMs) have caused negative environmental impacts. DFMs will …

The fate of plastic in the ocean environment–a minireview

C Wayman, H Niemann - Environmental Science: Processes & Impacts, 2021 - pubs.rsc.org
The presence of plastics in the marine environment poses a threat to ocean life and has
received much scientific and public attention in recent years. Plastics were introduced to the …

Newly emerging airborne pollutants: current knowledge of health impact of micro and nanoplastics

A Facciolà, G Visalli, M Pruiti Ciarello… - International journal of …, 2021 - mdpi.com
Plastics are ubiquitous persistent pollutants, forming the most representative material of the
Anthropocene. In the environment, they undergo wear and tear (ie, mechanical …

Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage

JH Woo, HJ Seo, JY Lee, I Lee, K Jeon, B Kim… - Particle and Fibre …, 2023 - Springer
Background Polypropylene (PP) is used in various products such as disposable containers,
spoons, and automobile parts. The disposable masks used for COVID-19 prevention mainly …