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[HTML][HTML] Atomic force microscopy observation and characterization of single virions and virus-like particles by nano-indentation
Highlights•Review of the most recent studies in Mechanical Virology, using AFM nano-
indentation.•Mechanics of structural capsid changes during maturation.•Uncoating …
indentation.•Mechanics of structural capsid changes during maturation.•Uncoating …
Breach: host membrane penetration and entry by nonenveloped viruses
Disruption of host membranes by nonenveloped viruses, which allows the nucleocapsid or
genome to enter the cytosol, is a mechanistically diverse process. Although the membrane …
genome to enter the cytosol, is a mechanistically diverse process. Although the membrane …
Dicistrovirus-host molecular interactions
Members of the family Dicistroviridae are small RNA viruses containing a monopartite
positive-sense RNA genome. Dicistroviruses mainly infect arthropods, causing diseases that …
positive-sense RNA genome. Dicistroviruses mainly infect arthropods, causing diseases that …
Free energies of the disassembly of viral capsids from a multiscale molecular simulation approach
Molecular simulations of large biological systems, such as viral capsids, remains a
challenging task in soft matter research. On one hand, coarse-grained (CG) models attempt …
challenging task in soft matter research. On one hand, coarse-grained (CG) models attempt …
MD simulations of viruslike particles with supra CG solvation affordable to desktop computers
Viruses are tremendously efficient molecular devices that optimize the packing of genetic
material using a minimalistic number of proteins to form a capsid or envelope that protects …
material using a minimalistic number of proteins to form a capsid or envelope that protects …
[HTML][HTML] Computational method for designing vaccines applied to virus-like particles (VLPs) as epitope carriers
Nonenveloped virus-like particles (VLPs) are self-assembled oligomeric structures
composed of one or more proteins that originate from diverse viruses. Because these VLPs …
composed of one or more proteins that originate from diverse viruses. Because these VLPs …
pyCapsid: Identifying dominant dynamics and quasi-rigid mechanical units in protein shells
Abstract Summary pyCapsid is a Python package developed to facilitate the characterization
of the dynamics and quasi-rigid mechanical units of protein shells and other protein …
of the dynamics and quasi-rigid mechanical units of protein shells and other protein …
Honey bee deformed wing virus structures reveal that conformational changes accompany genome release
The picornavirus-like deformed wing virus (DWV) has been directly linked to colony
collapse; however, little is known about the mechanisms of host attachment or entry for DWV …
collapse; however, little is known about the mechanisms of host attachment or entry for DWV …
[HTML][HTML] Virion structures and genome delivery of honeybee viruses
M Procházková, K Škubník, T Füzik… - Current opinion in …, 2020 - Elsevier
Highlights•Infections by dicistroviruses and iflaviruses are lethal for honeybees.•Capsids of
dicistroviruses and iflaviruses are organized with icosahedral symmetry.•Genome release of …
dicistroviruses and iflaviruses are organized with icosahedral symmetry.•Genome release of …
Virion structure of Israeli acute bee paralysis virus
E Mullapudi, A Přidal, L Pálková… - Journal of …, 2016 - journals.asm.org
The pollination services provided by the western honeybee (Apis mellifera) are critical for
agricultural production and the diversity of wild flowering plants. However, honeybees suffer …
agricultural production and the diversity of wild flowering plants. However, honeybees suffer …