Andrographolide, a diterpene lactone from Andrographis paniculata and its therapeutic promises in cancer

MT Islam, ES Ali, SJ Uddin, MA Islam, S Shaw, IN Khan… - Cancer letters, 2018 - Elsevier
The diterpene lactone andrographolide, isolated from Andrographis paniculata, has been
proven to possess several important protective biological activities, including antioxidant …

The anticancer properties of Salvia miltiorrhiza Bunge (Danshen): a systematic review

X Chen, J Guo, J Bao, J Lu… - Medicinal research …, 2014 - Wiley Online Library
Abstract Salvia miltiorrhiza Bunge (Danshen in Chinese) is a classical Huoxue Huayu (a
traditional Chinese medical term means promoting blood circulation and removing blood …

Potential mechanisms of action of dietary phytochemicals for cancer prevention by targeting cellular signaling transduction pathways

H Chen, RH Liu - Journal of agricultural and food chemistry, 2018 - ACS Publications
Cancer is a severe health problem that significantly undermines life span and quality.
Dietary approach helps provide preventive, nontoxic, and economical strategies against …

Naturally occurring coumestans from plants, their biological activities and therapeutic effects on human diseases

Y Tu, Y Yang, Y Li, C He - Pharmacological research, 2021 - Elsevier
Naturally occurring coumestans are known as a collection of plant-derived polycyclic
aromatic secondary metabolites which are characterized by the presence of an oxygen …

Anti-cancer agent: the labdane diterpenoid-andrographolide

R Tundis, JK Patra, M Bonesi, S Das, R Nath… - Plants, 2023 - mdpi.com
In spite of the progress in treatment strategies, cancer remains a major cause of death
worldwide. Therefore, the main challenge should be the early diagnosis of cancer and the …

Curcumin's beneficial effects on neuroblastoma: mechanisms, challenges, and potential solutions

K Zhai, A Brockmüller, P Kubatka, M Shakibaei… - Biomolecules, 2020 - mdpi.com
Curcumin, a natural polyphenolic compound derived from the South Asian turmeric plant
(Curcuma longa), has well-characterized antioxidant, anti-inflammatory, anti-protein …

Cholesterol-lowering phytochemicals: Targeting the mevalonate pathway for anticancer interventions

K Laka, L Makgoo, Z Mbita - Frontiers in Genetics, 2022 - frontiersin.org
There are a plethora of cancer causes and the road to fully understanding the
carcinogenesis process remains a dream that keeps changing. However, a list of role …

Aqueous Ethanolic Extract of Tinospora cordifolia as a Potential Candidate for Differentiation Based Therapy of Glioblastomas

R Mishra, G Kaur - PLoS One, 2013 - journals.plos.org
Glioblastomas are the most aggressive primary brain tumors and their heterogeneity and
complexity often renders them non responsive to various conventional treatments. Search …

Combinations of the antioxidants sulforaphane or curcumin and the conventional antineoplastics cisplatin or doxorubicin as prospects for anticancer chemotherapy

M Negrette-Guzman - European journal of pharmacology, 2019 - Elsevier
Drugs used in clinical oncology have narrow therapeutic indices with adverse toxicity often
involving oxidative damage. Chemoresistance to these conventional antineoplastics is …

[HTML][HTML] Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells

X Wang, J Deng, J Yuan, X Tang… - International …, 2017 - spandidos-publications.com
Glioblastoma is the most common brain cancer in adults. It represents one of the top ten
malignant tumors with an average survival time of nine months despite treatments with …