Reconstructing organisms in silico: genome-scale models and their emerging applications
Escherichia coli is considered to be the best-known microorganism given the large number
of published studies detailing its genes, its genome and the biochemical functions of its …
of published studies detailing its genes, its genome and the biochemical functions of its …
The role of the gut microbiota in colorectal cancer causation
EA Alhinai, GE Walton, DM Commane - International Journal of Molecular …, 2019 - mdpi.com
Here, we reviewed emerging evidence on the role of the microbial community in colorectal
carcinogenesis. A healthy gut microbiota promotes intestinal homeostasis and can exert anti …
carcinogenesis. A healthy gut microbiota promotes intestinal homeostasis and can exert anti …
Genome-scale metabolic modeling of the human microbiome in the era of personalized medicine
The human microbiome plays an important role in human health and disease. Meta-omics
analyses provide indispensable data for linking changes in microbiome composition and …
analyses provide indispensable data for linking changes in microbiome composition and …
A biochemically-interpretable machine learning classifier for microbial GWAS
Current machine learning classifiers have successfully been applied to whole-genome
sequencing data to identify genetic determinants of antimicrobial resistance (AMR), but they …
sequencing data to identify genetic determinants of antimicrobial resistance (AMR), but they …
A workflow for generating multi-strain genome-scale metabolic models of prokaryotes
Genome-scale models (GEMs) of bacterial strains' metabolism have been formulated and
used over the past 20 years. Recently, with the number of genome sequences exponentially …
used over the past 20 years. Recently, with the number of genome sequences exponentially …
The effects of diet and gut microbiota on the regulation of intestinal mucin glycosylation
Intestinal mucins glycosylation is regulated by host cues and environmental signals from the
microbiome and diets. However, the mechanisms responsible for the dialogue between …
microbiome and diets. However, the mechanisms responsible for the dialogue between …