In order to minimize expensive drug failures, is essential to determine potential activity,
toxicity and ADME problems as early as possible. In view of the large libraries of compounds …

Quantitative structure–activity relationship (QSAR) models are generated for biological
activity and toxicity in terms of global and local reactivity descriptors within a conceptual …

Abstract A dicyclohexyl (2‐sulfo‐9‐(3‐(4‐sulfophenyl) propyl)‐9H‐fluoren‐9‐yl)
phosphonium salt was synthesized in 64% overall yield in three steps from simple …

Many drugs with very different affinity to a large number of receptors are described. Thus, in
this work, we selected drug− target pairs (DTPs/nDTPs) of drugs with high affinity/nonaffinity …

There are many drugs described with very different affinity to a large number of receptors. In
this work, we selected drug− receptor pairs (DRPs) of affinity/nonaffinity drugs to …

There are many drugs described with very different affinity to a large number of receptors. In
this work, we selected Drug-Target pairs (DTPs/nDTPs) of drugs with high affinity/non-affinity …

The diseases caused by protozoan parasite are responsible for considerable mortality and
morbidity, affecting more than 500 million of people in the world. The epidemiological control …

There are many pairs of possible Drug–Proteins Interactions that may take place or not
(DPIs/nDPIs) between drugs with high affinity/non-affinity for different proteins. This fact …

Different regulatory agencies in food and drug administration and environmental protection
worldwide are employing quantitative structure–activity relationship (QSAR) models to fill the …

The development of the complex network graphs permits us to describe any real system
such as social, neural, computer or genetic networks by transforming real properties in …