Timing of lifespan influences on brain and cognition
Modifiable risk and protective factors for boosting brain and cognitive development and
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …
Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup
CR Jack Jr, JS Andrews, TG Beach… - Alzheimer's & …, 2024 - Wiley Online Library
Abstract The National Institute on Aging and the Alzheimer's Association convened three
separate work groups in 2011 and single work groups in 2012 and 2018 to create …
separate work groups in 2011 and single work groups in 2012 and 2018 to create …
Alzheimer's disease: exploring the landscape of cognitive decline
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
cognitive decline, memory loss, and impaired daily functioning. The pathology of AD is …
cognitive decline, memory loss, and impaired daily functioning. The pathology of AD is …
Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests
With the emergence of Alzheimer's disease (AD) disease-modifying therapies, identifying
patients who could benefit from these treatments becomes critical. In this study, we …
patients who could benefit from these treatments becomes critical. In this study, we …
Diagnostic accuracy of a plasma phosphorylated tau 217 immunoassay for Alzheimer disease pathology
Importance Phosphorylated tau (p-tau) is a specific blood biomarker for Alzheimer disease
(AD) pathology, with p-tau217 considered to have the most utility. However, availability of p …
(AD) pathology, with p-tau217 considered to have the most utility. However, availability of p …
Alzheimer disease as a clinical-biological construct—an International Working Group recommendation
Importance Since 2018, a movement has emerged to define Alzheimer disease (AD) as a
purely biological entity based on biomarker findings. The recent revision of the Alzheimer's …
purely biological entity based on biomarker findings. The recent revision of the Alzheimer's …
Revised criteria for the diagnosis and staging of Alzheimer's disease
CR Jack Jr, SJ Andrews, TG Beach, T Buracchio… - Nature medicine, 2024 - nature.com
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Blood biomarkers to detect Alzheimer disease in primary care and secondary care
Importance An accurate blood test for Alzheimer disease (AD) could streamline the
diagnostic workup and treatment of AD. Objective To prospectively evaluate a clinically …
diagnostic workup and treatment of AD. Objective To prospectively evaluate a clinically …
Plasma biomarker strategy for selecting patients with Alzheimer disease for antiamyloid immunotherapies
Importance Antiamyloid immunotherapies against Alzheimer disease (AD) are emerging.
Scalable, cost-effective tools will be needed to identify amyloid β (Aβ)–positive patients …
Scalable, cost-effective tools will be needed to identify amyloid β (Aβ)–positive patients …
Diagnosis of Alzheimer's disease using plasma biomarkers adjusted to clinical probability
Recently approved anti-amyloid immunotherapies for Alzheimer's disease (AD) require
evidence of amyloid-β pathology from positron emission tomography (PET) or cerebrospinal …
evidence of amyloid-β pathology from positron emission tomography (PET) or cerebrospinal …