As the professional antigen-presenting cells of the immune system, dendritic cells (DCs)
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …

The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

Dendritic cells (DCs) are potent and versatile antigen-presenting cells, and their ability to
migrate is key for the initiation of protective pro-inflammatory as well as tolerogenic immune …

Our understanding of allergic contact dermatitis mechanisms has progressed over the past
decade. Innate immune cells that are involved in the pathogenesis of allergic contact …

Our assumptions on the identity and functions of Langerhans cells (LCs) of the epidermis
have undergone considerable changes. Once thought to be prototypic representatives of the …

Immune cell populations in the skin are predominantly comprised of dendritic cells (DCs)
and macrophages. A lack of consensus regarding how to define these cell types has …

Dendritic cells (DCs) are a heterogeneous population playing a pivotal role in immune
responses and tolerance. DCs promote immune tolerance by participating in the negative …

Skin is the largest organ of the body with a complex network of multitude of cell types that
perform plastic and dynamic cellular communication to maintain several vital processes …

Atopic dermatitis, also known as atopic eczema, is a chronic inflammatory skin disease
characterized by red pruritic skin lesions, xerosis, ichthyosis, and skin pain. Among the …

In the last few decades, our understanding of Langerhans cells (LCs) has drastically
changed based on novel findings regarding the developmental origin and biological …