Background The clinical course of patients with moderate aortic stenosis (AS) remains
incompletely defined. Objectives This study sought to analyze the clinical course of …

Current guidelines recommend that clinical surveillance for patients with moderate aortic
stenosis (AS) and aortic valve replacement (AVR) may be considered if there is an indication …

Background: The potential benefit of transcatheter aortic valve replacement (TAVR) in
patients with nonsevere aortic stenosis (AS) and heart failure is controversial. This study …

Indications for transcatheter aortic valve replacement (TAVR) have steadily increased over
the last decade since the first trials including inoperable or very high risk patients. Thus …

BACKGROUND: Although the prognosis and management of severe aortic stenosis has
been extensively studied, the risk stratification and outcomes of patients with moderate aortic …

Background Afterload from moderate aortic stenosis (AS) may contribute to adverse
outcomes in patients with heart failure with reduced ejection fraction (HFrEF). Objectives The …

Background Neurohormonal modulation and afterload reduction are key for treatment of
heart failure with reduced ejection fraction (HFrEF). In HFrEF patients with concomitant …

Importance In patients with severe aortic stenosis and left ventricular ejection fraction (LVEF)
less than 50%, early LVEF improvement after transcatheter aortic valve replacement (TAVR) …

Patients with severe aortic stenosis (AS) may develop heart failure (HF), the presence of
which has traditionally been deemed as a final stage in AS progression with poor outcomes …

Objective To investigate the prognostic impact of left ventricular (LV) diastolic dysfunction in
patients with moderate aortic stenosis (AS) and preserved LV systolic function. Methods …