Breakthrough of extracellular vesicles in pathogenesis, diagnosis and treatment of osteoarthritis

Z Liu, Y Zhuang, L Fang, C Yuan, X Wang… - Bioactive …, 2022 - pmc.ncbi.nlm.nih.gov
Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …

[HTML][HTML] 3D bioprinting of hydrogels for cartilage tissue engineering

J Huang, J **ong, D Wang, J Zhang, L Yang, S Sun… - Gels, 2021 - mdpi.com
Three-dimensional (3D) bioprinting is an emerging technology based on 3D digital imaging
technology and multi-level continuous printing. The precise positioning of biological …

Comparison of the therapeutic effect of amniotic fluid stem cells and their exosomes on monoiodoacetate‐induced animal model of osteoarthritis

M Zavatti, F Beretti, F Casciaro, E Bertucci… - Biofactors, 2020 - Wiley Online Library
The cartilage tissue engineering associated with stem cell‐related therapies is becoming
very interesting since adult articular cartilage has limited intrinsic capacity for regeneration …

Mesenchymal stem/stromal cell secretome for lung regeneration: The long way through “pharmaceuticalization” for the best formulation

E Bari, I Ferrarotti, ML Torre, AG Corsico… - Journal of Controlled …, 2019 - Elsevier
Pulmonary acute and chronic diseases, such as chronic obstructive pulmonary disease,
pulmonary fibrosis and pulmonary hypertension, are considered to be major health issues …

Mesenchymal stem cell-derived exosomes as new remedy for the treatment of neurocognitive disorders

CR Harrell, A Volarevic, V Djonov… - International journal of …, 2021 - mdpi.com
Mesenchymal stem cell (MSC)-derived exosomes (MSC-Exo) are nano-sized extracellular
vesicles enriched with MSC-sourced neuroprotective and immunomodulatory microRNAs …

[HTML][HTML] Mesenchymal stem cells in soft tissue regenerative medicine: a comprehensive review

A Rehman, A Nigam, L Laino, D Russo, C Todisco… - Medicina, 2023 - mdpi.com
Soft tissue regeneration holds significant promise for addressing various clinical challenges,
ranging from craniofacial and oral tissue defects to blood vessels, muscle, and fibrous tissue …

Exploring the therapeutic potential of different sources of mesenchymal stem cells: a novel approach to combat burn wound infections

S Aliniay-Sharafshadehi, MH Yousefi… - Frontiers in …, 2024 - frontiersin.org
The most prevalent and harmful injuries are burns, which are still a major global health
problem. Burn injuries can cause issues because they boost the inflammatory and metabolic …

Therapeutic potential of mesenchymal stem cells and their secretome in the treatment of glaucoma

CR Harrell, C Fellabaum, A Arsenijevic… - Stem cells …, 2019 - Wiley Online Library
Glaucoma represents a group of progressive optic neuropathies characterized by gradual
loss of retinal ganglion cells (RGCs), the neurons that conduct visual information from the …

Mechanism of action and therapeutic effects of oxidative stress and stem cell-based materials in skin aging: Current evidence and future perspectives

H Qian, Y Shan, R Gong, D Lin, M Zhang… - … in Bioengineering and …, 2023 - frontiersin.org
Aging is associated with multiple degenerative diseases, including atherosclerosis,
osteoporosis, and Alzheimer's disease. As the most intuitive manifestation of aging, skin …

Utilizing stem cell-secreted molecules as a versatile toolbox for skin regenerative medicine

J Zheng, K Park, J Jang, D Son, J Park, J Kim… - Journal of Controlled …, 2024 - Elsevier
Stem cells are recognized as an important target and tool in regenerative engineering. In
this study, we explored the feasibility of engineering amniotic fluid-derived mesenchymal …