New drug delivery systems developed for brain targeting
The blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSF) are two of
the most complex and sophisticated concierges that defend the central nervous system …
the most complex and sophisticated concierges that defend the central nervous system …
[HTML][HTML] Current chemical, biological, and physiological views in the development of successful brain-targeted pharmaceutics
M Markowicz-Piasecka, A Markiewicz, P Darłak… - …, 2022 - Elsevier
One of the greatest challenges with successful pharmaceutical treatments of central nervous
system (CNS) diseases is the delivery of drugs into their target sites with appropriate …
system (CNS) diseases is the delivery of drugs into their target sites with appropriate …
Photosynthesis of hypericin in aqueous medium: A greener approach to prodrug strategy design in photodynamic therapy
PC de Souza Pereira, RS Goncalves… - Journal of Molecular …, 2020 - Elsevier
In line with environmental concerns, in this study we propose a new protocol to perform the
photosynthesis of Hypericin (Hyp) from protohypericin (Protohyp) in aqueous medium. The …
photosynthesis of Hypericin (Hyp) from protohypericin (Protohyp) in aqueous medium. The …
Codrugs: Optimum use through prodrugs
Selection of candidates for codrug designing is from same or different therapeutic
categories. Similarly, the constituents of codrug can act on the same or different biological …
categories. Similarly, the constituents of codrug can act on the same or different biological …