Harnessing endogenous stimuli for responsive materials in theranostics
Materials that respond to endogenous stimuli are being leveraged to enhance
spatiotemporal control in a range of biomedical applications from drug delivery to diagnostic …
spatiotemporal control in a range of biomedical applications from drug delivery to diagnostic …
Advanced liposome and polymersome-based drug delivery systems: Considerations for physicochemical properties, targeting strategies and stimuli-sensitive …
Liposomes and polymersomes are colloidal vesicles that are self-assembled from lipids and
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …
NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo
G Jia, Y Han, Y An, Y Ding, C He, X Wang, Q Tang - Biomaterials, 2018 - Elsevier
Currently, glioma treatment is limited by two main factors: timely detection at onset or relapse
and restriction of drugs by the blood–brain barrier (BBB) from entering the brain and …
and restriction of drugs by the blood–brain barrier (BBB) from entering the brain and …
Antibiotic-loaded nanoparticles targeted to the site of infection enhance antibacterial efficacy
Bacterial resistance to antibiotics has made it necessary to resort to using antibacterial drugs
that have considerable toxicities. Here, we show that conjugation of vancomycin-loaded …
that have considerable toxicities. Here, we show that conjugation of vancomycin-loaded …
Exosomal targeting and its potential clinical application
J He, W Ren, W Wang, W Han, L Jiang… - Drug Delivery and …, 2022 - Springer
Exosomes are extracellular vesicles secreted by a variety of living cells, which have a
certain degree of natural targeting as nano-carriers. Almost all exosomes released by cells …
certain degree of natural targeting as nano-carriers. Almost all exosomes released by cells …
Recent progress in functionalized and targeted polymersomes and chimeric polymeric nanotheranostic platforms for cancer therapy
The majority of advances in cancer therapy have been achieved based on developments in
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …
Cationic liposomes as vectors for nucleic acid and hydrophobic drug therapeutics
Cationic liposomes (CLs) are effective carriers of a variety of therapeutics. Their applications
as vectors of nucleic acids (NAs), from long DNA and mRNA to short interfering RNA …
as vectors of nucleic acids (NAs), from long DNA and mRNA to short interfering RNA …
Chemotactic synthetic vesicles: Design and applications in blood-brain barrier crossing
In recent years, scientists have created artificial microscopic and nanoscopic self-propelling
particles, often referred to as nano-or microswimmers, capable of mimicking biological …
particles, often referred to as nano-or microswimmers, capable of mimicking biological …
An iRGD-conjugated prodrug micelle with blood-brain-barrier penetrability for anti-glioma therapy
Various obstacles impede the chemotherapy efficiency of glioma in clinic, such as blood
brain barrier (BBB) and blood brain tumor barrier (BBTB). Ligand-mediated polymeric …
brain barrier (BBB) and blood brain tumor barrier (BBTB). Ligand-mediated polymeric …
Synthesis of block copolymers used in polymersome fabrication: Application in drug delivery
Amphiphilic block copolymers are common materials used for the fabrication of various
nanostructures with biomedical applications including nanocapsules, nanospheres, micelles …
nanostructures with biomedical applications including nanocapsules, nanospheres, micelles …