Microfluidic technology is creating powerful tools for cell biologists to control the complete
cellular microenvironment, leading to new questions and new discoveries. We review here …

Patch clamp electrophysiology has transformed research in the life sciences over the last
few decades. Since their inception, automatic patch clamp platforms have evolved …

The field of micro total analysis systems (μTAS), or “lab on a chip”, has continued to gain
maturity. The importance of μTAS is reflected in both the growing number and the improved …

This paper presents a microfluidic system for cell type classification using mechanical and
electrical measurements on single cells. Cells are aspirated continuously through a …

This paper presents a microfluidic device for simultaneous mechanical and electrical
characterization of single cells. The device performs two types of cellular characterization …

A device for continuous differential impedance analysis of single cells held by a
hydrodynamic cell trap** is presented. Measurements are accomplished by recording the …

Systems biology advocates the understanding of biology at the systems-level, which
requires massive information of correlations among individual components in complex …

Detection of chemical processes on a single molecule scale is the ultimate goal of sensitive
analytical assays. We recently reported the possibility to detect chemical modifications on …

Due to the cellular heterogeneity in multidrug resistance (MDR) cell populations, positive
drug effects on the modulation of MDR can be obscured in conventional methods, especially …

In order to understand information processing in neural circuits, it is necessary to detect both
electrical and chemical signaling with high spatial and temporal resolution. Although the …