The microtubule-based spindle orchestrates chromosome segregation during cell division.
Following more than a century of study, many components and pathways contributing to …

The mitotic spindle has a crucial role in ensuring the accurate segregation of chromosomes
into the two daughter cells during cell division, which is paramount for maintaining genome …

It has become clear that the role of centrosomes extends well beyond that of important
microtubule organizers. There is increasing evidence that they also function as coordination …

Centrosome amplification is a hallmark of cancer. However, despite significant progress in
recent years, we are still far from understanding how centrosome amplification affects …

We review recent advances in laser cell surgery, and investigate the working mechanisms of
femtosecond laser nanoprocessing in biomaterials with oscillator pulses of 80-MHz …

The organization of microtubule networks is crucial for controlling chromosome segregation
during cell division, for positioning and transport of different organelles, and for cell polarity …

Life depends on cell proliferation and the accurate segregation of chromosomes, which are
mediated by the microtubule (MT)-based mitotic spindle and∼ 200 essential MT-associated …

The microtubules that comprise mitotic spindles in animal cells are nucleated at
centrosomes and by spindle assembly factors that are activated in the vicinity of chromatin …

All eukaryotic cells prepare for cell division by forming a “mitotic spindle”—a bipolar machine
made from microtubules (MTs) and many associated proteins. This device organizes the …

Monastrol, a cell-permeable small molecule inhibitor of the mitotic kinesin, Eg5, arrests cells
in mitosis with monoastral spindles. Here, we use monastrol to probe mitotic mechanisms …