[HTML][HTML] Japanese encephalitis—the prospects for new treatments

L Turtle, T Solomon - Nature Reviews Neurology, 2018 - nature.com
Japanese encephalitis is a mosquito-borne disease that occurs in Asia and is caused by
Japanese encephalitis virus (JEV), a member of the genus Flavivirus. Although many …

Pathobiology of Japanese encephalitis virus infection

KB Sharma, S Vrati, M Kalia - Molecular aspects of medicine, 2021 - Elsevier
Japanese encephalitis virus (JEV) is a flavivirus, spread by the bite of carrier Culex
mosquitoes. The subsequent disease caused is Japanese encephalitis (JE), which is the …

Structures of the Zika virus envelope protein and its complex with a flavivirus broadly protective antibody

L Dai, J Song, X Lu, YQ Deng, AM Musyoki, H Cheng… - Cell host & …, 2016 - cell.com
Zika virus (ZIKV), a mosquito-borne flavivirus, is a current global public health concern. The
flavivirus envelope (E) glycoprotein is responsible for virus entry and represents a major …

Structure of the thermally stable Zika virus

VA Kostyuchenko, EXY Lim, S Zhang, G Fibriansah… - Nature, 2016 - nature.com
Zika virus (ZIKV), formerly a neglected pathogen, has recently been associated with
microcephaly in fetuses, and with Guillian–Barré syndrome in adults. Here we present the …

Near-atomic structure of Japanese encephalitis virus reveals critical determinants of virulence and stability

X Wang, SH Li, L Zhu, QG Nian, S Yuan, Q Gao… - Nature …, 2017 - nature.com
Although several different flaviviruses may cause encephalitis, Japanese encephalitis virus
is the most significant, being responsible for thousands of deaths each year in Asia. The …

The antigenic structure of Zika virus and its relation to other flaviviruses: implications for infection and immunoprophylaxis

FX Heinz, K Stiasny - Microbiology and Molecular Biology …, 2017 - journals.asm.org
Zika virus was discovered∼ 70 years ago in Uganda and maintained a low profile as a
human disease agent in Africa and Asia. Only recently has it caused explosive outbreaks in …

Viruses and miRNAs: more friends than foes

P Bruscella, S Bottini, C Baudesson… - Frontiers in …, 2017 - frontiersin.org
There is evidence that eukaryotic miRNAs (hereafter called host miRNAs) play a role in the
replication and propagation of viruses. Expression or targeting of host miRNAs can be …

Structures and functions of the envelope glycoprotein in flavivirus infections

X Zhang, R Jia, H Shen, M Wang, Z Yin, A Cheng - Viruses, 2017 - mdpi.com
Flaviviruses are enveloped, single-stranded RNA viruses that widely infect many animal
species. The envelope protein, a structural protein of flavivirus, plays an important role in …

Affinity-restricted memory B cells dominate recall responses to heterologous flaviviruses

R Wong, JA Belk, J Govero, JL Uhrlaub, D Reinartz… - Immunity, 2020 - cell.com
Memory B cells (MBCs) can respond to heterologous antigens either by molding new
specificities through secondary germinal centers (GCs) or by selecting preexisting clones …

Molecular detection and characterisation of the first Japanese encephalitis virus belonging to genotype IV acquired in Australia

C Sikazwe, MJ Neave, A Michie, P Mileto… - PLoS Neglected …, 2022 - journals.plos.org
Background A fatal case of Japanese encephalitis (JE) occurred in a resident of the Tiwi
Islands, in the Northern Territory of Australia in February 2021, preceding the large JE …