Peptide-based vaccines for tuberculosis

W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022‏ - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

Allergic diseases: a comprehensive review on risk factors, immunological mechanisms, link with COVID-19, potential treatments, and role of allergen bioinformatics

FM Aldakheel - International journal of environmental research and …, 2021‏ - mdpi.com
The prevalence of allergic diseases is regarded as one of the key challenges in health
worldwide. Although the precise mechanisms underlying this rapid increase in prevalence …

In silico design of a novel multi-epitope vaccine against HCV infection through immunoinformatics approaches

S Ahmad, FM Demneh, B Rehman, TN Almanaa… - International journal of …, 2024‏ - Elsevier
Infection with the hepatitis C virus (HCV) is one of the causes of liver cancer, which is the
world's sixth most prevalent and third most lethal cancer. The current treatments do not …

In silico design and immunoinformatics analysis of a universal multi-epitope vaccine against monkeypox virus

S Sanami, S Nazarian, S Ahmad, E Raeisi… - Plos one, 2023‏ - journals.plos.org
Monkeypox virus (MPXV) outbreaks have been reported in various countries worldwide;
however, there is no specific vaccine against MPXV. In this study, therefore, we employed …

Designing a novel multi‑epitope vaccine against Ebola virus using reverse vaccinology approach

M Alizadeh, H Amini-Khoei, S Tahmasebian… - Scientific reports, 2022‏ - nature.com
Ebola virus (EBOV) is a dangerous zoonotic infectious disease. To date, more than 25 EBOV
outbreaks have been documented, the majority of which have occurred in Central Africa …

Designing a Next-Generation Multiepitope-Based Vaccine against Staphylococcus aureus Using Reverse Vaccinology Approaches

SR Mahapatra, J Dey, TK Raj, N Misra, M Suar - Pathogens, 2023‏ - mdpi.com
Staphylococcus aureus is a human bacterial pathogen that can cause a wide range of
symptoms. As virulent and multi-drug-resistant strains of S. aureus have evolved, invasive S …

Immunoinformatics and structural aided approach to develop multi-epitope based subunit vaccine against Mycobacterium tuberculosis

G Sethi, RP Varghese, AK Lakra, SS Nayak… - Scientific Reports, 2024‏ - nature.com
Tuberculosis is a highly contagious disease caused by Mycobacterium tuberculosis (Mtb),
which is one of the prominent reasons for the death of millions worldwide. The bacterium …

Immunoinformatics-guided approach for designing a pan-proteome multi-epitope subunit vaccine against African swine fever virus

AM Simbulan, EC Banico, EMJS Sira… - Scientific Reports, 2024‏ - nature.com
Despite being identified over a hundred years ago, there is still no commercially available
vaccine for the highly contagious and deadly African swine fever virus (ASFV). This study …

Vaccine development for bacterial pathogens: Advances, challenges and prospects

IE Mba, HC Sharndama… - Tropical Medicine & …, 2023‏ - Wiley Online Library
The advent and use of antimicrobials have played a key role in treating potentially life‐
threatening infectious diseases, improving health, and saving the lives of millions of people …

Emerging strategies and therapeutic innovations for combating drug resistance in Staphylococcus aureus strains: A comprehensive review

M Gopikrishnan, S Haryini - Journal of Basic Microbiology, 2024‏ - Wiley Online Library
In recent years, antibiotic therapy has encountered significant challenges due to the rapid
emergence of multidrug resistance among bacteria responsible for life‐threatening …