Droplet microfluidics has revolutionized the study of single cells. The ability to
compartmentalize cells within picoliter droplets in microfluidic devices has opened up a wide …

Microfluidic systems are pervasive in many areas of experimental science, but what are the
real advantages of this technology? We describe some of the features and properties that …

Recent advances in cellular profiling have demonstrated substantial heterogeneity in the
behaviour of cells once deemed'identical', challenging fundamental notions of …

Many new techniques and materials have been applied to microfluidic systems in the past
decade, and integrated microfluidic chips have become powerful platforms for realizing …

The field of single-cell genomics is advancing rapidly and is generating many new insights
into complex biological systems, ranging from the diversity of microbial ecosystems to the …

Understanding molecular, cellular, genetic and functional heterogeneity of tumors at the
single-cell level has become a major challenge for cancer research. The microfluidic …

Whole-genome amplification (WGA) for next-generation sequencing has seen wide
applications in biology and medicine when characterization of the genome of a single cell is …

The inherent heterogeneity in cell populations has become of great interest and importance
as analytical techniques have improved over the past decades. With the advent of …

The commonly existing cellular heterogeneity plays a critical role in biological processes
such as embryonic development, cell differentiation, and disease progress. Single‐cell …

Single-cell whole-genome sequencing (WGS) is critical for characterizing dynamic
intercellular changes in DNA. Current sample preparation technologies for single-cell WGS …