Osteoarthritis (OA) is the most common degenerative joint disease and a major cause of
pain and disability in adult individuals. The etiology of OA includes joint injury, obesity …

Osteoarthritis (OA) is the most common form of arthritis in the US, and a leading cause of
disability. It is typically defined in epidemiologic studies on the basis of radiographic findings …

Osteoarthritis is the most common musculoskeletal disease and the leading cause of
disability globally. Here, we performed a genome-wide association study for osteoarthritis …

Abstract The Estonian Biobank cohort is a volunteer-based sample of the Estonian resident
adult population (aged≥ 18 years). The current number of participants—close to 52000 …

There are many known risk factors for chronic pain conditions, yet the biological
underpinnings that link these factors to abnormal processing of painful signals are only just …

Osteoarthritis has a highly negative impact on quality of life because of the associated pain
and loss of joint function. Here we describe the largest meta-analysis so far of osteoarthritis …

Research into the molecular genetics of osteoarthritis (OA) has been substantially bolstered
in the past few years by the implementation of powerful genome-wide scans that have …

Chronic pain conditions are multifactorial disorders with a high frequency in the population.
Their pathophysiology is often unclear, and treatment is inefficient. During the last 20 years …

Osteoarthritis is the most common form of arthritis and is a major cause of pain and disability
in the elderly. To search for sequence variants that confer risk of osteoarthritis of the hand …

Objective To perform a genome‐wide DNA methylation study to identify DNA methylation
changes in osteoarthritic (OA) cartilage tissue. Methods The contribution of differentially …