Traditional medicine has provided a basis for health care and disease treatment to Chinese
people for millennia, and herbal medicines are regulated as drug products in China …

Glucuronidation and sulfation are the most typical phase II metabolic reactions of drugs. The
resulting glucuronide and sulfate conjugates are generally considered inactive and safe …

Background Glycyrrhizin (GL) is a major active constituent of licorice root (Glycyrrhiza
glabra) that is considered one of the oldest and most frequently employed botanicals in …

Thyroid hormones (THs) and TH receptor-beta (TRβ) reduce hepatic triglycerides, indicating
a therapeutic potential for TH analogs in liver steatosis. To avoid adverse extrahepatic …

LianhuaQingwen capsule, prepared from an herbal combination, is officially recommended
as treatment for COVID-19 in China. Of the serial pharmacokinetic investigations we …

Translational pharmacological research on traditional medicines lays the foundation for
precisely understanding how the medicines function in the body to deliver therapeutic …

Introduction Non-small cell lung cancer (NSCLC) patients are particularly vulnerable to the
Coronavirus Disease-2019 (COVID-19). Currently, no anti-NSCLC/COVID-19 treatment …

Direct oral anticoagulants, such as apixaban and rivaroxaban, are important for the
treatment and prophylaxis of venous thromboembolism and to reduce the risk of stroke and …

The present study focuses on predicting the pharmacokinetics and toxicological endpoints of
the widely used intensive sweeteners for preventing and management of diabetes …

Natural medicine has been widely used for clinical treatment and health care in many
countries and regions. Additionally, extracting active ingredients from traditional Chinese …